4q4g

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==Structure of the Resuscitation Promoting Factor Interacting protein RipA mutated at C383==
==Structure of the Resuscitation Promoting Factor Interacting protein RipA mutated at C383==
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<StructureSection load='4q4g' size='340' side='right' caption='[[4q4g]], [[Resolution|resolution]] 0.97&Aring;' scene=''>
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<StructureSection load='4q4g' size='340' side='right'caption='[[4q4g]], [[Resolution|resolution]] 0.97&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4q4g]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q4G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Q4G FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4q4g]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q4G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Q4G FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4q4n|4q4n]], [[4q4t|4q4t]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.97&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q4g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q4g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4q4g RCSB], [http://www.ebi.ac.uk/pdbsum/4q4g PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4q4g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q4g OCA], [https://pdbe.org/4q4g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4q4g RCSB], [https://www.ebi.ac.uk/pdbsum/4q4g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4q4g ProSAT]</span></td></tr>
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<table>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RIPA_MYCTU RIPA_MYCTU] Peptidoglycan endopeptidase that cleaves the bond between D-glutamate and meso-diaminopimelate. Binds and degrades high-molecular weight peptidoglycan from a number of Actinobacteria; activity is increased in the presence of RpfB and inhibited by PBP1A (ponA1). Required for normal separation of daughter cells after cell division and for cell wall integrity. Required for host cell invasion and intracellular survival in host macrophages.<ref>PMID:16495549</ref> <ref>PMID:17919286</ref> <ref>PMID:18463693</ref> <ref>PMID:20826344</ref> <ref>PMID:21864539</ref>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Berisio, R.]]
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[[Category: Large Structures]]
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[[Category: Alpha-beta]]
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Cell wall hydrolase]]
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[[Category: Berisio R]]
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[[Category: Hydrolase]]
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Current revision

Structure of the Resuscitation Promoting Factor Interacting protein RipA mutated at C383

PDB ID 4q4g

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