3wqr
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of pfdxr complexed with inhibitor-12== | |
| + | <StructureSection load='3wqr' size='340' side='right'caption='[[3wqr]], [[Resolution|resolution]] 1.97Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3wqr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_HB3 Plasmodium falciparum HB3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WQR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WQR FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.97Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=LSX:[(1S)-4-[HYDROXY(METHYL)AMINO]-1-(4-METHOXYPHENYL)-4-OXOBUTYL]PHOSPHONIC+ACID'>LSX</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wqr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wqr OCA], [https://pdbe.org/3wqr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wqr RCSB], [https://www.ebi.ac.uk/pdbsum/3wqr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wqr ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DXR_PLAFX DXR_PLAFX] Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).<ref>PMID:10477522</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[DXP reductoisomerase 3D Structures|DXP reductoisomerase 3D Structures]] | |
| - | + | == References == | |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Plasmodium falciparum HB3]] | ||
| + | [[Category: Tanaka N]] | ||
| + | [[Category: Umeda T]] | ||
Current revision
Crystal structure of pfdxr complexed with inhibitor-12
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