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3wvz
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Hikeshi, a new nuclear transport receptor of Hsp70== | |
| - | + | <StructureSection load='3wvz' size='340' side='right'caption='[[3wvz]], [[Resolution|resolution]] 1.88Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3wvz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WVZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WVZ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.88Å</td></tr> | |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wvz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wvz OCA], [https://pdbe.org/3wvz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wvz RCSB], [https://www.ebi.ac.uk/pdbsum/3wvz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wvz ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/HIKES_HUMAN HIKES_HUMAN] Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus.<ref>PMID:22541429</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Choi S]] | ||
| + | [[Category: Hong RH]] | ||
| + | [[Category: Imamoto N]] | ||
| + | [[Category: Kose S]] | ||
| + | [[Category: Lee SJ]] | ||
| + | [[Category: Park IY]] | ||
| + | [[Category: Son SY]] | ||
| + | [[Category: Song J]] | ||
| + | [[Category: Watanabe A]] | ||
| + | [[Category: Yamashita E]] | ||
Current revision
Crystal structure of Hikeshi, a new nuclear transport receptor of Hsp70
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Categories: Homo sapiens | Large Structures | Choi S | Hong RH | Imamoto N | Kose S | Lee SJ | Park IY | Son SY | Song J | Watanabe A | Yamashita E
