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3ww0

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'''Unreleased structure'''
 
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The entry 3ww0 is ON HOLD until Paper Publication
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==Crystal structure of F97A mutant, a new nuclear transport receptor of Hsp70==
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<StructureSection load='3ww0' size='340' side='right'caption='[[3ww0]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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Authors: Song, J., Kose, S., Watanabe, A., Son, S.Y., Choi, S., Hong, R.H., Yamashita, E., Park, I.Y., Imamoto, N., Lee, S.J.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3ww0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WW0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WW0 FirstGlance]. <br>
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Description: To be published
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ww0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ww0 OCA], [https://pdbe.org/3ww0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ww0 RCSB], [https://www.ebi.ac.uk/pdbsum/3ww0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ww0 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/HIKES_HUMAN HIKES_HUMAN] Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus.<ref>PMID:22541429</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Choi S]]
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[[Category: Hong RH]]
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[[Category: Imamoto N]]
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[[Category: Kose S]]
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[[Category: Lee SJ]]
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[[Category: Park IY]]
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[[Category: Son SY]]
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[[Category: Song J]]
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[[Category: Watanabe A]]
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[[Category: Yamashita E]]

Current revision

Crystal structure of F97A mutant, a new nuclear transport receptor of Hsp70

PDB ID 3ww0

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