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1hg7

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==HIGH RESOLUTION STRUCTURE OF HPLC-12 TYPE III ANTIFREEZE PROTEIN FROM OCEAN POUT MACROZOARCES AMERICANUS==
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<StructureSection load='1hg7' size='340' side='right' caption='[[1hg7]], [[Resolution|resolution]] 1.15&Aring;' scene=''>
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==High resolution structure of HPLC-12 type III antifreeze protein from Ocean Pout Macrozoarces americanus==
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<StructureSection load='1hg7' size='340' side='right'caption='[[1hg7]], [[Resolution|resolution]] 1.15&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1hg7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Zoarces_americanus Zoarces americanus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HG7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HG7 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1hg7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Zoarces_americanus Zoarces americanus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HG7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HG7 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.15&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ame|1ame]], [[1b7i|1b7i]], [[1b7j|1b7j]], [[1b7k|1b7k]], [[1ekl|1ekl]], [[1gzi|1gzi]], [[1jab|1jab]], [[1kde|1kde]], [[1kdf|1kdf]], [[1msi|1msi]], [[1msj|1msj]], [[2ame|2ame]], [[2jia|2jia]], [[2msi|2msi]], [[2msj|2msj]], [[2spg|2spg]], [[3ame|3ame]], [[3msi|3msi]], [[4ame|4ame]], [[4msi|4msi]], [[5msi|5msi]], [[6ame|6ame]], [[6msi|6msi]], [[7ame|7ame]], [[7msi|7msi]], [[8ame|8ame]], [[8msi|8msi]], [[9ame|9ame]], [[9msi|9msi]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RECOMBINANT TYPE III AFP HPURCE 10 FRACTION 12 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=8199 Zoarces americanus])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hg7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hg7 OCA], [https://pdbe.org/1hg7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hg7 RCSB], [https://www.ebi.ac.uk/pdbsum/1hg7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hg7 ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hg7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hg7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1hg7 RCSB], [http://www.ebi.ac.uk/pdbsum/1hg7 PDBsum]</span></td></tr>
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</table>
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<table>
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== Function ==
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[https://www.uniprot.org/uniprot/ANP12_ZOAAM ANP12_ZOAAM] Contributes to protect fish blood from freezing at subzero sea water temperatures. Lowers the blood freezing point. Binds to nascent ice crystals and prevents further growth.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hg/1hg7_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hg/1hg7_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1hg7 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 1hg7" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Antifreeze protein|Antifreeze protein]]
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*[[Antifreeze protein 3D structures|Antifreeze protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Zoarces americanus]]
[[Category: Zoarces americanus]]
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[[Category: Antson, A A.]]
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[[Category: Antson AA]]
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[[Category: Buckley, S L.]]
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[[Category: Buckley SL]]
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[[Category: Caves, L S.D.]]
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[[Category: Caves LSD]]
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[[Category: Hubbard, R E.]]
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[[Category: Hubbard RE]]
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[[Category: Lewis, S.]]
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[[Category: Lewis S]]
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[[Category: Lillford, P J.]]
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[[Category: Lillford PJ]]
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[[Category: Roper, D I.]]
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[[Category: Roper DI]]
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[[Category: Smith, D J.]]
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[[Category: Smith DJ]]
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[[Category: Verma, C S.]]
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[[Category: Verma CS]]
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[[Category: Antifreeze protein]]
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[[Category: Ice-binding protein]]
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[[Category: Macrozoarces americanus]]
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[[Category: Ocean pout]]
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Current revision

High resolution structure of HPLC-12 type III antifreeze protein from Ocean Pout Macrozoarces americanus

PDB ID 1hg7

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