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1o7y

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==CRYSTAL STRUCTURE OF IP-10 M-FORM==
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<StructureSection load='1o7y' size='340' side='right' caption='[[1o7y]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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==Crystal structure of IP-10 M-form==
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<StructureSection load='1o7y' size='340' side='right'caption='[[1o7y]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1o7y]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O7Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1O7Y FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1o7y]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O7Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1O7Y FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1lv9|1lv9]], [[1o7z|1o7z]], [[1o80|1o80]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1o7y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1o7y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1o7y RCSB], [http://www.ebi.ac.uk/pdbsum/1o7y PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1o7y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1o7y OCA], [https://pdbe.org/1o7y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1o7y RCSB], [https://www.ebi.ac.uk/pdbsum/1o7y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1o7y ProSAT]</span></td></tr>
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<table>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CXL10_HUMAN CXL10_HUMAN] Chemotactic for monocytes and T-lymphocytes. Binds to CXCR3.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o7/1o7y_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o7/1o7y_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1o7y ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 1o7y" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[C-X-C motif chemokine|C-X-C motif chemokine]]
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*[[C-X-C motif chemokine 3D structures|C-X-C motif chemokine 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Acharya, K R.]]
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[[Category: Homo sapiens]]
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[[Category: Holloway, D E.]]
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[[Category: Large Structures]]
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[[Category: Papageorgiou, A C.]]
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[[Category: Acharya KR]]
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[[Category: Swaminathan, G J.]]
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[[Category: Holloway DE]]
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[[Category: Chemokine]]
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[[Category: Papageorgiou AC]]
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[[Category: Chemotaxis]]
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[[Category: Swaminathan GJ]]
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[[Category: Inflammatory response]]
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[[Category: Interferon induction]]
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Current revision

Crystal structure of IP-10 M-form

PDB ID 1o7y

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