1mn7

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==NDP kinase mutant (H122G;N119S;F64W) in complex with aBAZTTP==
==NDP kinase mutant (H122G;N119S;F64W) in complex with aBAZTTP==
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<StructureSection load='1mn7' size='340' side='right' caption='[[1mn7]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
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<StructureSection load='1mn7' size='340' side='right'caption='[[1mn7]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1mn7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Dictyostelium_discoideum Dictyostelium discoideum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MN7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MN7 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1mn7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Dictyostelium_discoideum Dictyostelium discoideum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MN7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MN7 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ABT:3-AZIDO-3-DEOXY-THYMIDINE-5-ALPHA+BORANO+TRIPHOSPHATE'>ABT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1lwx|1lwx]], [[1f6t|1f6t]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ABT:3-AZIDO-3-DEOXY-THYMIDINE-5-ALPHA+BORANO+TRIPHOSPHATE'>ABT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Nucleoside-diphosphate_kinase Nucleoside-diphosphate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.6 2.7.4.6] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mn7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mn7 OCA], [https://pdbe.org/1mn7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mn7 RCSB], [https://www.ebi.ac.uk/pdbsum/1mn7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mn7 ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1mn7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mn7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1mn7 RCSB], [http://www.ebi.ac.uk/pdbsum/1mn7 PDBsum]</span></td></tr>
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</table>
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<table>
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== Function ==
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[https://www.uniprot.org/uniprot/NDKC_DICDI NDKC_DICDI]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mn/1mn7_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mn/1mn7_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mn7 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 1mn7" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Nucleoside diphosphate kinase|Nucleoside diphosphate kinase]]
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*[[Nucleoside diphosphate kinase 3D structures|Nucleoside diphosphate kinase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Dictyostelium discoideum]]
[[Category: Dictyostelium discoideum]]
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[[Category: Nucleoside-diphosphate kinase]]
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[[Category: Large Structures]]
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[[Category: Chen, y.]]
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[[Category: Chen y]]
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[[Category: Deville-bonne, d.]]
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[[Category: Deville-bonne d]]
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[[Category: Gallois-montbrun, s.]]
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[[Category: Gallois-montbrun s]]
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[[Category: Giacomoni-fernandes, v.]]
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[[Category: Giacomoni-fernandes v]]
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[[Category: Janin, j.]]
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[[Category: Janin j]]
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[[Category: Morera, s.]]
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[[Category: Morera s]]
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[[Category: Mulard, l.]]
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[[Category: Mulard l]]
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[[Category: Schneider, b.]]
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[[Category: Schneider b]]
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[[Category: Veron, m.]]
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[[Category: Veron m]]
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[[Category: Ndp kinase-abazttp complex]]
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[[Category: Transferase]]
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Current revision

NDP kinase mutant (H122G;N119S;F64W) in complex with aBAZTTP

PDB ID 1mn7

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