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1oew

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==ATOMIC RESOLUTION STRUCTURE OF NATIVE ENDOTHIAPEPSIN==
==ATOMIC RESOLUTION STRUCTURE OF NATIVE ENDOTHIAPEPSIN==
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<StructureSection load='1oew' size='340' side='right' caption='[[1oew]], [[Resolution|resolution]] 0.90&Aring;' scene=''>
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<StructureSection load='1oew' size='340' side='right'caption='[[1oew]], [[Resolution|resolution]] 0.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1oew]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OEW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OEW FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1oew]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OEW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OEW FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SER:SERINE'>SER</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=THR:THREONINE'>THR</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.9&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SUI:(3-AMINO-2,5-DIOXO-1-PYRROLIDINYL)ACETIC+ACID'>SUI</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SER:SERINE'>SER</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=SUI:(3-AMINO-2,5-DIOXO-1-PYRROLIDINYL)ACETIC+ACID'>SUI</scene>, <scene name='pdbligand=THR:THREONINE'>THR</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1e5o|1e5o]], [[1e80|1e80]], [[1e81|1e81]], [[1e82|1e82]], [[1eed|1eed]], [[1ent|1ent]], [[1epl|1epl]], [[1epm|1epm]], [[1epn|1epn]], [[1epo|1epo]], [[1epp|1epp]], [[1epq|1epq]], [[1epr|1epr]], [[1er8|1er8]], [[1gkt|1gkt]], [[1gvt|1gvt]], [[1gvu|1gvu]], [[1gvv|1gvv]], [[1gvw|1gvw]], [[1gvx|1gvx]], [[1od1|1od1]], [[1oex|1oex]], [[2er0|2er0]], [[2er6|2er6]], [[2er7|2er7]], [[2er9|2er9]], [[3er3|3er3]], [[3er5|3er5]], [[4ape|4ape]], [[4er1|4er1]], [[4er2|4er2]], [[4er4|4er4]], [[5er1|5er1]], [[5er2|5er2]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1oew FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1oew OCA], [https://pdbe.org/1oew PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1oew RCSB], [https://www.ebi.ac.uk/pdbsum/1oew PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1oew ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endothiapepsin Endothiapepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.22 3.4.23.22] </span></td></tr>
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</table>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1oew FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1oew OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1oew RCSB], [http://www.ebi.ac.uk/pdbsum/1oew PDBsum]</span></td></tr>
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== Function ==
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<table>
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[https://www.uniprot.org/uniprot/CARP_CRYPA CARP_CRYPA]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oe/1oew_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oe/1oew_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1oew ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 1oew" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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</StructureSection>
</StructureSection>
[[Category: Cryphonectria parasitica]]
[[Category: Cryphonectria parasitica]]
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[[Category: Endothiapepsin]]
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[[Category: Large Structures]]
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[[Category: Coates, L.]]
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[[Category: Coates L]]
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[[Category: Cooper, J B.]]
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[[Category: Cooper JB]]
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[[Category: Erskine, P T.]]
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[[Category: Erskine PT]]
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[[Category: Gill, R S.]]
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[[Category: Gill RS]]
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[[Category: Mall, S.]]
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[[Category: Mall S]]
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[[Category: Myles, D A.A.]]
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[[Category: Myles DAA]]
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[[Category: Wood, S P.]]
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[[Category: Wood SP]]
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[[Category: Anisotropic refinement]]
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[[Category: Aspartic proteinase mechanism]]
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[[Category: Atomic resolution]]
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[[Category: Hydrolase]]
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[[Category: Succinimide]]
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Current revision

ATOMIC RESOLUTION STRUCTURE OF NATIVE ENDOTHIAPEPSIN

PDB ID 1oew

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