1lu2

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==DOLICHOS BIFLORUS SEED LECTIN IN COMPLEX WITH THE BLOOD GROUP A TRISACCHARIDE==
==DOLICHOS BIFLORUS SEED LECTIN IN COMPLEX WITH THE BLOOD GROUP A TRISACCHARIDE==
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<StructureSection load='1lu2' size='340' side='right' caption='[[1lu2]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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<StructureSection load='1lu2' size='340' side='right'caption='[[1lu2]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1lu2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Vigna_unguiculata_subsp._cylindrica Vigna unguiculata subsp. cylindrica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LU2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1LU2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1lu2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Vigna_unguiculata_subsp._cylindrica Vigna unguiculata subsp. cylindrica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LU2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LU2 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1lu2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lu2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1lu2 RCSB], [http://www.ebi.ac.uk/pdbsum/1lu2 PDBsum]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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<table>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lu2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lu2 OCA], [https://pdbe.org/1lu2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lu2 RCSB], [https://www.ebi.ac.uk/pdbsum/1lu2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lu2 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LEC1_VIGUC LEC1_VIGUC] Metalloglycoprotein, containing Ca, Mg, Mn, and Zn and the carbohydrates galactose, glucosamine, mannose, and fucose. It agglutinates erythrocytes of blood group A1. Has a high preference for GalNAc over Gal.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lu/1lu2_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lu/1lu2_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lu2 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 1lu2" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Vigna unguiculata subsp. cylindrica]]
[[Category: Vigna unguiculata subsp. cylindrica]]
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[[Category: Bouckaert, J.]]
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[[Category: Bouckaert J]]
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[[Category: Etzler, M E.]]
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[[Category: Etzler ME]]
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[[Category: Fernandez, E.]]
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[[Category: Fernandez E]]
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[[Category: Hamelryck, T W.]]
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[[Category: Hamelryck TW]]
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[[Category: Imberty, A.]]
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[[Category: Imberty A]]
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[[Category: Loris, R.]]
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[[Category: Loris R]]
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[[Category: Strecker, G.]]
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[[Category: Strecker G]]
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[[Category: Wyns, L.]]
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[[Category: Wyns L]]
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[[Category: Dolichos biflorus seed lectin]]
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[[Category: Lectin]]
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[[Category: Legume lectin]]
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[[Category: Sugar binding]]
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Current revision

DOLICHOS BIFLORUS SEED LECTIN IN COMPLEX WITH THE BLOOD GROUP A TRISACCHARIDE

PDB ID 1lu2

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OCA

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