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1w2m

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==CA-SUBSTITUTED FORM OF E. COLI AMINOPEPTIDASE P==
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<StructureSection load='1w2m' size='340' side='right' caption='[[1w2m]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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==Ca-substituted form of E. coli aminopeptidase P==
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<StructureSection load='1w2m' size='340' side='right'caption='[[1w2m]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1w2m]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W2M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1W2M FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1w2m]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W2M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1W2M FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1a16|1a16]], [[1jaw|1jaw]], [[1m35|1m35]], [[1n51|1n51]], [[1w7v|1w7v]], [[1wbq|1wbq]], [[1wl6|1wl6]], [[1wl9|1wl9]], [[1wlr|1wlr]], [[2bh3|2bh3]], [[2bha|2bha]], [[2bhb|2bhb]], [[2bhc|2bhc]], [[2bhd|2bhd]], [[2bn7|2bn7]], [[2bws|2bws]], [[2bwt|2bwt]], [[2bwu|2bwu]], [[2bwv|2bwv]], [[2bww|2bww]], [[2bwx|2bwx]], [[2bwy|2bwy]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1w2m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w2m OCA], [https://pdbe.org/1w2m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1w2m RCSB], [https://www.ebi.ac.uk/pdbsum/1w2m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1w2m ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PEPP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
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</table>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Xaa-Pro_aminopeptidase Xaa-Pro aminopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.9 3.4.11.9] </span></td></tr>
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== Function ==
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1w2m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w2m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1w2m RCSB], [http://www.ebi.ac.uk/pdbsum/1w2m PDBsum]</span></td></tr>
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[https://www.uniprot.org/uniprot/AMPP_ECOLI AMPP_ECOLI]
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<table>
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== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w2/1w2m_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w2/1w2m_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1w2m ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 1w2m" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Aminopeptidase|Aminopeptidase]]
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*[[Aminopeptidase 3D structures|Aminopeptidase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Xaa-Pro aminopeptidase]]
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[[Category: Large Structures]]
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[[Category: Bond, C S.]]
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[[Category: Bond CS]]
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[[Category: Freeman, H C.]]
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[[Category: Freeman HC]]
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[[Category: Graham, S C.]]
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[[Category: Graham SC]]
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[[Category: Guss, J M.]]
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[[Category: Guss JM]]
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[[Category: Hydrolase]]
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[[Category: Metalloenzyme]]
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[[Category: Metalloprotease]]
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[[Category: Pita- bread fold]]
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[[Category: Proline-specific peptidase]]
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Current revision

Ca-substituted form of E. coli aminopeptidase P

PDB ID 1w2m

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