1yn6

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==Crystal structure of a mouse MHC class I protein, H2-Db, in complex with a peptide from the influenza A acid polymerase==
==Crystal structure of a mouse MHC class I protein, H2-Db, in complex with a peptide from the influenza A acid polymerase==
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<StructureSection load='1yn6' size='340' side='right' caption='[[1yn6]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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<StructureSection load='1yn6' size='340' side='right'caption='[[1yn6]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1yn6]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YN6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YN6 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1yn6]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Influenza_A_virus_(A/swine/Iowa/15/1930(H1N1)) Influenza A virus (A/swine/Iowa/15/1930(H1N1))] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YN6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YN6 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1yn7|1yn7]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA-directed_RNA_polymerase RNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.48 2.7.7.48] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yn6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yn6 OCA], [https://pdbe.org/1yn6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yn6 RCSB], [https://www.ebi.ac.uk/pdbsum/1yn6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yn6 ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yn6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yn6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1yn6 RCSB], [http://www.ebi.ac.uk/pdbsum/1yn6 PDBsum]</span></td></tr>
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</table>
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<table>
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== Function ==
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[https://www.uniprot.org/uniprot/HA11_MOUSE HA11_MOUSE] Involved in the presentation of foreign antigens to the immune system.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yn/1yn6_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yn/1yn6_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1yn6 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Beta-2 microglobulin|Beta-2 microglobulin]]
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*[[Beta-2 microglobulin 3D structures|Beta-2 microglobulin 3D structures]]
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*[[Major histocompatibility complex|Major histocompatibility complex]]
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*[[MHC 3D structures|MHC 3D structures]]
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*[[MHC I 3D structures|MHC I 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: RNA-directed RNA polymerase]]
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[[Category: Doherty PC]]
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[[Category: Doherty, P C.]]
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[[Category: Dunstone MA]]
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[[Category: Dunstone, M A.]]
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[[Category: Kedzierska K]]
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[[Category: Gruta, N L.La.]]
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[[Category: Komodromou H]]
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[[Category: Kedzierska, K.]]
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[[Category: La Gruta NL]]
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[[Category: Komodromou, H.]]
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[[Category: McCluskey J]]
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[[Category: McCluskey, J.]]
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[[Category: Purcell AW]]
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[[Category: Purcell, A W.]]
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[[Category: Rossjohn J]]
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[[Category: Rossjohn, J.]]
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[[Category: Turner SJ]]
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[[Category: Turner, S J.]]
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[[Category: Walden H]]
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[[Category: Walden, H.]]
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[[Category: Webb AI]]
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[[Category: Webb, A I.]]
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[[Category: Webby R]]
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[[Category: Webby, R.]]
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[[Category: Xie W]]
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[[Category: Xie, W.]]
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[[Category: H2-db]]
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[[Category: Immune system]]
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[[Category: Influenza some]]
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[[Category: Mhc class 1]]
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[[Category: Peptide of acid polymerase]]
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Current revision

Crystal structure of a mouse MHC class I protein, H2-Db, in complex with a peptide from the influenza A acid polymerase

PDB ID 1yn6

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