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1uvn

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==THE STRUCTURAL BASIS FOR RNA SPECIFICITY AND CA2 INHIBITION OF AN RNA-DEPENDENT RNA POLYMERASE PHI6P2 CA2+ INHIBITION COMPLEX==
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<StructureSection load='1uvn' size='340' side='right' caption='[[1uvn]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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==The structural basis for RNA specificity and Ca2 inhibition of an RNA-dependent RNA polymerase phi6p2 ca2+ inhibition complex==
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<StructureSection load='1uvn' size='340' side='right'caption='[[1uvn]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1uvn]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UVN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UVN FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1uvn]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_virus_phi6 Pseudomonas virus phi6] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UVN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UVN FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1hhs|1hhs]], [[1hht|1hht]], [[1hi0|1hi0]], [[1hi1|1hi1]], [[1hi8|1hi8]], [[1uvi|1uvi]], [[1uvj|1uvj]], [[1uvk|1uvk]], [[1uvl|1uvl]], [[1uvm|1uvm]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uvn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uvn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1uvn RCSB], [http://www.ebi.ac.uk/pdbsum/1uvn PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uvn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uvn OCA], [https://pdbe.org/1uvn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uvn RCSB], [https://www.ebi.ac.uk/pdbsum/1uvn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uvn ProSAT]</span></td></tr>
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<table>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RDRP_BPPH6 RDRP_BPPH6]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 1uvn" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[RNA polymerase|RNA polymerase]]
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*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bamford, D.]]
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[[Category: Large Structures]]
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[[Category: Butcher, S.]]
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[[Category: Pseudomonas virus phi6]]
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[[Category: Grimes, J M.]]
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[[Category: Synthetic construct]]
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[[Category: Makeyev, E V.]]
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[[Category: Bamford D]]
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[[Category: Salgado, P S.]]
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[[Category: Butcher S]]
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[[Category: Stuart, D I.]]
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[[Category: Grimes JM]]
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[[Category: Gtp]]
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[[Category: Makeyev EV]]
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[[Category: Mn]]
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[[Category: Salgado PS]]
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[[Category: Polymerase]]
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[[Category: Stuart DI]]
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[[Category: Rna-dependent rna polymerase ca inhibition complex with 6nt rna oligonucleotide]]
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[[Category: Transcription]]
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The structural basis for RNA specificity and Ca2 inhibition of an RNA-dependent RNA polymerase phi6p2 ca2+ inhibition complex

PDB ID 1uvn

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