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1w4n

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==AGAO COVALENT COMPLEX WITH TRANYLCYPROMINE==
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<StructureSection load='1w4n' size='340' side='right' caption='[[1w4n]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
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==AGAO covalent complex with Tranylcypromine==
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<StructureSection load='1w4n' size='340' side='right'caption='[[1w4n]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1w4n]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arthrobacter_globiformis Arthrobacter globiformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W4N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1W4N FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1w4n]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arthrobacter_globiformis Arthrobacter globiformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W4N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1W4N FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TCQ:(1S,2R)-N-{(1E)-5-[(2S)-2-AMINO-2-CARBOXYETHYL]-2-HYDROXY-4-OXOCYCLOHEXA-2,5-DIEN-1-YLIDENE}-2-PHENYLCYCLOPROPANAMINIUM'>TCQ</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TCQ:(1S,2R)-N-{(1E)-5-[(2S)-2-AMINO-2-CARBOXYETHYL]-2-HYDROXY-4-OXOCYCLOHEXA-2,5-DIEN-1-YLIDENE}-2-PHENYLCYCLOPROPANAMINIUM'>TCQ</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1av4|1av4]], [[1avk|1avk]], [[1avl|1avl]], [[1iqx|1iqx]], [[1iqy|1iqy]], [[1iu7|1iu7]], [[1ivu|1ivu]], [[1ivv|1ivv]], [[1ivw|1ivw]], [[1ivx|1ivx]], [[1rjo|1rjo]], [[1sih|1sih]], [[1sii|1sii]], [[1ui7|1ui7]], [[1ui8|1ui8]], [[1w5z|1w5z]], [[1w6c|1w6c]], [[1w6g|1w6g]], [[1wmn|1wmn]], [[1wmo|1wmo]], [[1wmp|1wmp]], [[2bt3|2bt3]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1w4n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w4n OCA], [https://pdbe.org/1w4n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1w4n RCSB], [https://www.ebi.ac.uk/pdbsum/1w4n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1w4n ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Oxidoreductase Oxidoreductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.3.21 and 1.4.3.22 1.4.3.21 and 1.4.3.22] </span></td></tr>
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</table>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1w4n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w4n OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1w4n RCSB], [http://www.ebi.ac.uk/pdbsum/1w4n PDBsum]</span></td></tr>
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== Function ==
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<table>
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[https://www.uniprot.org/uniprot/PAOX_ARTGO PAOX_ARTGO]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w4/1w4n_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w4/1w4n_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1w4n ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 1w4n" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Copper Amine Oxidase|Copper Amine Oxidase]]
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*[[Copper amine oxidase 3D structures|Copper amine oxidase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Arthrobacter globiformis]]
[[Category: Arthrobacter globiformis]]
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[[Category: Oxidoreductase]]
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[[Category: Large Structures]]
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[[Category: Dooley, D M.]]
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[[Category: Dooley DM]]
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[[Category: Duff, A P.]]
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[[Category: Duff AP]]
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[[Category: Freeman, H C.]]
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[[Category: Freeman HC]]
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[[Category: Guss, J M.]]
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[[Category: Guss JM]]
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[[Category: Juda, G A.]]
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[[Category: Juda GA]]
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[[Category: Langley, D B.]]
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[[Category: Langley DB]]
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[[Category: Shepard, E M.]]
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[[Category: Shepard EM]]
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[[Category: Trambaiolo, D M.]]
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[[Category: Trambaiolo DM]]
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[[Category: Amine oxidase]]
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[[Category: Arthrobacter globiformi]]
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[[Category: Copper containing]]
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[[Category: Inhibited]]
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[[Category: Metal-binding]]
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[[Category: Oxidoreductase]]
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[[Category: Quinone]]
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[[Category: Tcp]]
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[[Category: Tcq]]
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[[Category: Tranylcypromine]]
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Current revision

AGAO covalent complex with Tranylcypromine

PDB ID 1w4n

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