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1s73

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==Crystal Structure of Mesopone Cytochrome c Peroxidase (R-isomer) [MpCcP-R]==
==Crystal Structure of Mesopone Cytochrome c Peroxidase (R-isomer) [MpCcP-R]==
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<StructureSection load='1s73' size='340' side='right' caption='[[1s73]], [[Resolution|resolution]] 1.53&Aring;' scene=''>
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<StructureSection load='1s73' size='340' side='right'caption='[[1s73]], [[Resolution|resolution]] 1.53&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1s73]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S73 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1S73 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1s73]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S73 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1S73 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMI:FE-(4-MESOPORPHYRINONE)-R-ISOMER'>FMI</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.53&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2cyp|2cyp]], [[1kok|1kok]], [[1sbm|1sbm]], [[1sdq|1sdq]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMI:FE-(4-MESOPORPHYRINONE)-R-ISOMER'>FMI</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CCP1, CCP, CPO, YKR066C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1s73 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s73 OCA], [https://pdbe.org/1s73 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1s73 RCSB], [https://www.ebi.ac.uk/pdbsum/1s73 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1s73 ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cytochrome-c_peroxidase Cytochrome-c peroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.5 1.11.1.5] </span></td></tr>
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</table>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1s73 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s73 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1s73 RCSB], [http://www.ebi.ac.uk/pdbsum/1s73 PDBsum]</span></td></tr>
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== Function ==
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<table>
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[https://www.uniprot.org/uniprot/CCPR_YEAST CCPR_YEAST] Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/s7/1s73_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/s7/1s73_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1s73 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Cytochrome c peroxidase|Cytochrome c peroxidase]]
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*[[Cytochrome c peroxidase 3D structures|Cytochrome c peroxidase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Cytochrome-c peroxidase]]
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[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Bhaskar, B.]]
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[[Category: Bhaskar B]]
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[[Category: Choen, M S.]]
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[[Category: Choen MS]]
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[[Category: Farmer, P J.]]
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[[Category: Farmer PJ]]
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[[Category: Immoos, C E.]]
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[[Category: Immoos CE]]
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[[Category: Poulos, T L.]]
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[[Category: Poulos TL]]
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[[Category: Sulc, F.]]
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[[Category: Sulc F]]
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[[Category: Bifunctional catalyst]]
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[[Category: Cyctochrome c peroxidase]]
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[[Category: Cytochorme oxidase]]
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[[Category: Mesoporphyrin]]
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[[Category: Nitrite reductase]]
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[[Category: Oxidoreductase]]
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[[Category: Proximal loop]]
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[[Category: Trp191 radical]]
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Current revision

Crystal Structure of Mesopone Cytochrome c Peroxidase (R-isomer) [MpCcP-R]

PDB ID 1s73

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