1pm3

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==MTH1859==
==MTH1859==
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<StructureSection load='1pm3' size='340' side='right' caption='[[1pm3]], [[Resolution|resolution]] 3.15&Aring;' scene=''>
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<StructureSection load='1pm3' size='340' side='right'caption='[[1pm3]], [[Resolution|resolution]] 3.15&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1pm3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PM3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1PM3 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1pm3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PM3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PM3 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1pm3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pm3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1pm3 RCSB], [http://www.ebi.ac.uk/pdbsum/1pm3 PDBsum], [http://www.topsan.org/Proteins/NESGC/1pm3 TOPSAN]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.15&#8491;</td></tr>
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<table>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pm3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pm3 OCA], [https://pdbe.org/1pm3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pm3 RCSB], [https://www.ebi.ac.uk/pdbsum/1pm3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pm3 ProSAT], [https://www.topsan.org/Proteins/NESGC/1pm3 TOPSAN]</span></td></tr>
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<div style="background-color:#fffaf0;">
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</table>
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== Publication Abstract from PubMed ==
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== Function ==
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MTH1859 from Methanobacterium thermoautotrophicum is a 77 residue protein representing a conserved family of functionally uncharacterized proteins. We solved the crystal structure of MTH1859 by single wavelength anomalous diffraction phasing using selenomethionine labeled protein. MTH1859 adopts a mainly anti-parallel all-beta-fold. The beta-sheet is heavily bent to form a U-structure that is closed through a loop. The monomer structure possesses similarities to the photoreaction center (PRC) domain fold, but the protein employs a unique oligomerization scheme. Two monomers of MTH1859 occupy the asymmetric unit and dimerize in a head-to-head fashion. Crystal packing interactions identify a second protein-protein interaction interface at the MTH1859 tails which can simultaneously bind two partner molecules. These interactions lead to the formation of a honeycomb structure and suggest that the family of MTH1859-like proteins might function as adapters for protein complex assembly.
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[https://www.uniprot.org/uniprot/O27887_METTH O27887_METTH]
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Crystal structure of the putative adapter protein MTH1859.,Ye H, Chen TC, Xu X, Pennycooke M, Wu H, Steegborn C J Struct Biol. 2004 Nov;148(2):251-6. PMID:15477104<ref>PMID:15477104</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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== References ==
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<references/>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Methanothermobacter thermautotrophicus]]
[[Category: Methanothermobacter thermautotrophicus]]
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[[Category: NESG, Northeast Structural Genomics Consortium.]]
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[[Category: Steegborn C]]
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[[Category: Steegborn, C.]]
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[[Category: Wu H]]
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[[Category: Wu, H.]]
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[[Category: Ye H]]
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[[Category: Ye, H.]]
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[[Category: Nesg]]
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[[Category: Northeast structural genomics consortium]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Structural genomic]]
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[[Category: Unknown function]]
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Current revision

MTH1859

PDB ID 1pm3

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