1t75

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==Crystal structure of Escherichia coli beta carbonic anhydrase==
==Crystal structure of Escherichia coli beta carbonic anhydrase==
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<StructureSection load='1t75' size='340' side='right' caption='[[1t75]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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<StructureSection load='1t75' size='340' side='right'caption='[[1t75]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1t75]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T75 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1T75 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1t75]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T75 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1T75 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">YADF, B0126, SF0123, S0125 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1t75 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t75 OCA], [https://pdbe.org/1t75 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1t75 RCSB], [https://www.ebi.ac.uk/pdbsum/1t75 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1t75 ProSAT], [https://www.topsan.org/Proteins/BSGC/1t75 TOPSAN]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1t75 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t75 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1t75 RCSB], [http://www.ebi.ac.uk/pdbsum/1t75 PDBsum], [http://www.topsan.org/Proteins/BSGC/1t75 TOPSAN]</span></td></tr>
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</table>
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<table>
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== Function ==
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[https://www.uniprot.org/uniprot/CAN_ECOLI CAN_ECOLI]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/t7/1t75_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/t7/1t75_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1t75 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Carbonic anhydrase|Carbonic anhydrase]]
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*[[Carbonic anhydrase 3D structures|Carbonic anhydrase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Carbonate dehydratase]]
 
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: BSGC, Berkeley Structural Genomics Center.]]
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[[Category: Large Structures]]
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[[Category: Jancarik, J.]]
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[[Category: Jancarik J]]
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[[Category: Kim, R.]]
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[[Category: Kim R]]
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[[Category: Kim, S H.]]
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[[Category: Kim S-H]]
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[[Category: Oganesyan, V.]]
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[[Category: Oganesyan V]]
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[[Category: Berkeley structural genomics center]]
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[[Category: Bsgc structure funded by nih]]
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[[Category: Carbon dioxide reversible hydrating enzyme]]
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[[Category: Lyase]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Structural genomic]]
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Current revision

Crystal structure of Escherichia coli beta carbonic anhydrase

PDB ID 1t75

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