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2e4l

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==Thermodynamic and Structural Analysis of Thermolabile RNase HI from Shewanella oneidensis MR-1==
==Thermodynamic and Structural Analysis of Thermolabile RNase HI from Shewanella oneidensis MR-1==
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<StructureSection load='2e4l' size='340' side='right' caption='[[2e4l]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<StructureSection load='2e4l' size='340' side='right'caption='[[2e4l]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2e4l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Shewanella_oneidensis Shewanella oneidensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E4L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2E4L FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2e4l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Shewanella_oneidensis_MR-1 Shewanella oneidensis MR-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E4L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E4L FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rnhA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=70863 Shewanella oneidensis])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribonuclease_H Ribonuclease H], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.26.4 3.1.26.4] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e4l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e4l OCA], [https://pdbe.org/2e4l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e4l RCSB], [https://www.ebi.ac.uk/pdbsum/2e4l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e4l ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2e4l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e4l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2e4l RCSB], [http://www.ebi.ac.uk/pdbsum/2e4l PDBsum]</span></td></tr>
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</table>
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<table>
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== Function ==
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[https://www.uniprot.org/uniprot/RNH_SHEON RNH_SHEON] Endonuclease that specifically degrades the RNA of RNA-DNA hybrids (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e4/2e4l_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e4/2e4l_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2e4l ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2e4l" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Ribonuclease|Ribonuclease]]
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*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Ribonuclease H]]
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[[Category: Large Structures]]
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[[Category: Shewanella oneidensis]]
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[[Category: Shewanella oneidensis MR-1]]
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[[Category: Chon, H.]]
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[[Category: Chon H]]
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[[Category: Kanaya, S.]]
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[[Category: Kanaya S]]
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[[Category: Koga, Y.]]
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[[Category: Koga Y]]
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[[Category: Matsumura, H.]]
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[[Category: Matsumura H]]
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[[Category: Tadokoro, T.]]
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[[Category: Tadokoro T]]
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[[Category: Takano, K.]]
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[[Category: Takano K]]
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[[Category: You, D J.]]
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[[Category: You DJ]]
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[[Category: Endoribonuclease]]
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[[Category: Hydrolase]]
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[[Category: Rnase hi]]
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[[Category: Shewanella oneidensis mr-1]]
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Current revision

Thermodynamic and Structural Analysis of Thermolabile RNase HI from Shewanella oneidensis MR-1

PDB ID 2e4l

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