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2iii
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==Crystal structure of the adenosylmethionine decarboxylase (aq_254) from aquifex aeolicus vf5== | ==Crystal structure of the adenosylmethionine decarboxylase (aq_254) from aquifex aeolicus vf5== | ||
| - | <StructureSection load='2iii' size='340' side='right' caption='[[2iii]], [[Resolution|resolution]] 2.30Å' scene=''> | + | <StructureSection load='2iii' size='340' side='right'caption='[[2iii]], [[Resolution|resolution]] 2.30Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2iii]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2iii]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus_VF5 Aquifex aeolicus VF5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2III OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2III FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iii FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iii OCA], [https://pdbe.org/2iii PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iii RCSB], [https://www.ebi.ac.uk/pdbsum/2iii PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iii ProSAT], [https://www.topsan.org/Proteins/RSGI/2iii TOPSAN]</span></td></tr> | |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </table> |
| - | <table> | + | == Function == |
| + | [https://www.uniprot.org/uniprot/SPEH_AQUAE SPEH_AQUAE] Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ii/2iii_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ii/2iii_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2iii ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Aquifex aeolicus VF5]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Baba | + | [[Category: Baba S]] |
| - | [[Category: Ebihara | + | [[Category: Ebihara A]] |
| - | [[Category: Jeyakanthan | + | [[Category: Jeyakanthan J]] |
| - | [[Category: Kanaujia | + | [[Category: Kanaujia SP]] |
| - | [[Category: Kuramitsu | + | [[Category: Kuramitsu S]] |
| - | + | [[Category: Sekar K]] | |
| - | + | [[Category: Shinkai A]] | |
| - | [[Category: Sekar | + | [[Category: Shiro Y]] |
| - | [[Category: Shinkai | + | [[Category: Vasuki Ranjani C]] |
| - | [[Category: Shiro | + | [[Category: Yokoyama S]] |
| - | [[Category: | + | |
| - | [[Category: | + | |
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Current revision
Crystal structure of the adenosylmethionine decarboxylase (aq_254) from aquifex aeolicus vf5
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