2h6y
From Proteopedia
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==Crystal Structure of Thioredoxin Mutant E48D in Hexagonal (p61) Space Group==  | ==Crystal Structure of Thioredoxin Mutant E48D in Hexagonal (p61) Space Group==  | ||
| - | <StructureSection load='2h6y' size='340' side='right' caption='[[2h6y]], [[Resolution|resolution]] 2.40Å' scene=''>  | + | <StructureSection load='2h6y' size='340' side='right'caption='[[2h6y]], [[Resolution|resolution]] 2.40Å' scene=''>  | 
== Structural highlights ==  | == Structural highlights ==  | ||
| - | <table><tr><td colspan='2'>[[2h6y]] is a 2 chain structure with sequence from [  | + | <table><tr><td colspan='2'>[[2h6y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H6Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2H6Y FirstGlance]. <br>  | 
| - | </td></tr><tr><td class="sblockLbl"><b>[[  | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr>  | 
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>  | |
| - | <tr><td class="sblockLbl"><b>[[  | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2h6y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h6y OCA], [https://pdbe.org/2h6y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2h6y RCSB], [https://www.ebi.ac.uk/pdbsum/2h6y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2h6y ProSAT]</span></td></tr>  | 
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[  | + | </table>  | 
| - | <table>  | + | == Function ==  | 
| + | [https://www.uniprot.org/uniprot/THIO_ECOLI THIO_ECOLI] Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.  | ||
== Evolutionary Conservation ==  | == Evolutionary Conservation ==  | ||
[[Image:Consurf_key_small.gif|200px|right]]  | [[Image:Consurf_key_small.gif|200px|right]]  | ||
Check<jmol>  | Check<jmol>  | ||
  <jmolCheckbox>  |   <jmolCheckbox>  | ||
| - |     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h6/2h6y_consurf.spt"</scriptWhenChecked>  | + |     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h6/2h6y_consurf.spt"</scriptWhenChecked>  | 
| - |     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/  | + |     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>  | 
    <text>to colour the structure by Evolutionary Conservation</text>  |     <text>to colour the structure by Evolutionary Conservation</text>  | ||
  </jmolCheckbox>  |   </jmolCheckbox>  | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/  | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2h6y ConSurf].  | 
<div style="clear:both"></div>  | <div style="clear:both"></div>  | ||
==See Also==  | ==See Also==  | ||
| - | *[[Thioredoxin|Thioredoxin]]  | + | *[[Thioredoxin 3D structures|Thioredoxin 3D structures]]  | 
__TOC__  | __TOC__  | ||
</StructureSection>  | </StructureSection>  | ||
[[Category: Escherichia coli]]  | [[Category: Escherichia coli]]  | ||
| - | [[Category: Gavira  | + | [[Category: Large Structures]]  | 
| - | [[Category: Godoy-Ruiz  | + | [[Category: Gavira JA]]  | 
| - | [[Category: Ibarra-Molero  | + | [[Category: Godoy-Ruiz R]]  | 
| - | [[Category: Sanchez-Ruiz  | + | [[Category: Ibarra-Molero B]]  | 
| - | + | [[Category: Sanchez-Ruiz JM]]  | |
| - | + | ||
Current revision
Crystal Structure of Thioredoxin Mutant E48D in Hexagonal (p61) Space Group
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