2k62
From Proteopedia
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==NMR solution structure of the supramolecular adduct between a liver cytosolic bile acid binding protein and a bile acid-based Gd(III)-chelate== | ==NMR solution structure of the supramolecular adduct between a liver cytosolic bile acid binding protein and a bile acid-based Gd(III)-chelate== | ||
| - | <StructureSection load='2k62' size='340' side='right' caption='[[2k62 | + | <StructureSection load='2k62' size='340' side='right'caption='[[2k62]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2k62]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2k62]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K62 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K62 FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ITL:(3ALPHA,5ALPHA,8ALPHA)-3-[(N,N-BIS{2-[BIS(CARBOXYMETHYL)AMINO]ETHYL}-L-GAMMA-GLUTAMYL)AMINO]CHOLAN-24-OIC+ACID'>ITL</scene>, <scene name='pdbligand=YB:YTTERBIUM+(III)+ION'>YB</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ITL:(3ALPHA,5ALPHA,8ALPHA)-3-[(N,N-BIS{2-[BIS(CARBOXYMETHYL)AMINO]ETHYL}-L-GAMMA-GLUTAMYL)AMINO]CHOLAN-24-OIC+ACID'>ITL</scene>, <scene name='pdbligand=YB:YTTERBIUM+(III)+ION'>YB</scene></td></tr> | |
| - | <tr | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k62 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k62 OCA], [https://pdbe.org/2k62 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k62 RCSB], [https://www.ebi.ac.uk/pdbsum/2k62 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k62 ProSAT]</span></td></tr> |
| - | + | </table> | |
| - | <table> | + | == Function == |
| + | [https://www.uniprot.org/uniprot/FABPL_CHICK FABPL_CHICK] Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport. Binds 2 molecules of cholate per subunit. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k6/2k62_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k6/2k62_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2k62 ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 2k62" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Fatty acid-binding protein|Fatty acid-binding protein]] | + | *[[Fatty acid-binding protein 3D structures|Fatty acid-binding protein 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Gallus gallus]] | [[Category: Gallus gallus]] | ||
| - | [[Category: Aime | + | [[Category: Large Structures]] |
| - | [[Category: Assfalg | + | [[Category: Aime S]] |
| - | [[Category: Gianolio | + | [[Category: Assfalg M]] |
| - | [[Category: Molinari | + | [[Category: Gianolio E]] |
| - | [[Category: Ragona | + | [[Category: Molinari H]] |
| - | [[Category: Tomaselli | + | [[Category: Ragona L]] |
| - | [[Category: Zanzoni | + | [[Category: Tomaselli S]] |
| - | + | [[Category: Zanzoni S]] | |
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Current revision
NMR solution structure of the supramolecular adduct between a liver cytosolic bile acid binding protein and a bile acid-based Gd(III)-chelate
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Categories: Gallus gallus | Large Structures | Aime S | Assfalg M | Gianolio E | Molinari H | Ragona L | Tomaselli S | Zanzoni S
