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1zxk

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==Crystal Structure of Cadherin8 EC1 domain==
==Crystal Structure of Cadherin8 EC1 domain==
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<StructureSection load='1zxk' size='340' side='right' caption='[[1zxk]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<StructureSection load='1zxk' size='340' side='right'caption='[[1zxk]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1zxk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZXK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZXK FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1zxk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZXK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZXK FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1zvn|1zvn]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Cdh8 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zxk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zxk OCA], [https://pdbe.org/1zxk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zxk RCSB], [https://www.ebi.ac.uk/pdbsum/1zxk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zxk ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zxk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zxk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1zxk RCSB], [http://www.ebi.ac.uk/pdbsum/1zxk PDBsum]</span></td></tr>
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</table>
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<table>
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== Function ==
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[https://www.uniprot.org/uniprot/CADH8_MOUSE CADH8_MOUSE] Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zx/1zxk_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zx/1zxk_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1zxk ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 1zxk" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Cadherin|Cadherin]]
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*[[Cadherin 3D structures|Cadherin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Arkus, N.]]
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[[Category: Arkus N]]
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[[Category: Bahna, F.]]
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[[Category: Bahna F]]
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[[Category: Chen, C P.]]
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[[Category: Chen CP]]
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[[Category: Ciatto, C.]]
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[[Category: Ciatto C]]
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[[Category: Honig, B.]]
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[[Category: Honig B]]
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[[Category: Jessell, T M.]]
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[[Category: Jessell TM]]
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[[Category: Patel, S D.]]
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[[Category: Patel SD]]
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[[Category: Price, S R.]]
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[[Category: Price SR]]
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[[Category: Rajebhosale, M.]]
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[[Category: Rajebhosale M]]
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[[Category: Schieren, I.]]
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[[Category: Schieren I]]
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[[Category: Shapiro, L.]]
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[[Category: Shapiro L]]
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[[Category: Cadherin]]
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[[Category: Cell adhesion]]
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[[Category: Strand dimer]]
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Current revision

Crystal Structure of Cadherin8 EC1 domain

PDB ID 1zxk

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