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2w1x

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The interdependence of wavelength, redundancy and dose in sulfur SAD experiments: 1.284 A wavelength 360 images data

Structural highlights

2w1x is a 1 chain structure with sequence from Gallus gallus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:	,
Related:	1w6z, 1kxx, 4lyo, 3lyo, 1kip, 1t6v, 1ic7, 1vds, 1lzt, 1kir, 1lys, 1e8l, 1bwj, 132l, 1yil, 1heo, 1sfg, 1kxw, 2c8o, 1yl1, 1sf4, 1g7l, 1ior, 1h87, 1ljg, 3lyt, 1iot, 1dpx, 1v7s, 1ja6, 1jis, 1ir8, 2w1m, 1uic, 1ykz, 1xgq, 1uie, 1lji, 1lj3, 8lyz, 1dpw, 1bwi, 2iff, 2lyo, 1g7h, 1jj0, 1lks, 1rfp, 5lyt, 1sfb, 1jiy, 1ir7, 1iee, 1xei, 1xek, 1hel, 1at6, 1ljf, 1mlc, 1f10, 2b5z, 1lsz, 193l, 1ljk, 1sq2, 6lyt, 1vdq, 1zmy, 1lje, 2d91, 1b2k, 1lze, 1aki, 1uia, 1hen, 1yik, 1xfp, 2d6b, 1lpi, 1ndg, 1lsd, 1flw, 2blx, 6lyz, 1lsg, 1nbz, 4lyt, 3hfm, 1ved, 1jit, 1lzn, 1wtn, 1uuz, 1lyz, 1ja2, 2d4i, 2fbb, 2lym, 1fdl, 1lz9, 1lse, 1lzh, 1gxx, 1lsm, 1jj3, 3lym, 7lyz, 1yky, 1heq, 1kiq, 1t3p, 1uih, 1kxy, 2lzh, 2w1l, 1g7j, 1b0d, 2bly, 1bhz, 1her, 1wtm, 1hep, 1ioq, 1nby, 1jtt, 1qio, 1lza, 1ps5, 1xgp, 1gwd, 1jpo, 1v7t, 1h6m, 2a7d, 1j1p, 1dqj, 2c8p, 1z55, 1ljj, 1lsb, 1f0w, 1flq, 1lzg, 1lzc, 1jj1, 1rcm, 1yqv, 1uid, 1hsx, 1bgi, 1lzd, 1lcn, 1hew, 2cds, 2vb1, 2aub, 1uib, 1hf4, 1j1x, 1ir9, 1rjc, 1ios, 2cgi, 1uc0, 1azf, 1ljh, 1ic4, 4lyz, 1gpq, 2a6u, 2d4k, 1xej, 1ja7, 1mel, 1ri8, 1uig, 1bvx, 1qtk, 1c10, 1lkr, 1lyo, 1n4f, 1hsw, 1g7m, 1jto, 2w1y, 1sf7, 1lsf, 1fn5, 5lyz, 2d4j, 3lzt, 1c08, 1ndm, 1sf6, 3lyz, 1bvk, 1uif, 1vau, 2lyz, 1fly, 1lma, 1j1o, 1hc0, 1yl0, 2lzt, 4lzt, 1a2y, 1uco, 1lsy, 1p2c, 1ic5, 1gxv, 5lym, 1lsa, 1ua6, 1at5, 1hem, 1lj4, 1vfb, 1f3j, 1vat, 1ja4, 2a7f, 4lym, 1flu, 194l, 1lz8, 1ykx, 2hfm, 1vdt, 1bwh, 1io5, 1lsn, 1g7i, 1lzb, 2bpu, 1lsc, 1vdp
Activity:	Lysozyme, with EC number 3.2.1.17
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.^[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Publication Abstract from PubMed

In the last decade, the popularity of sulfur SAD anomalous dispersion experiments has spread rapidly among synchrotron users as a quick and streamlined way of solving the phase problem in macromolecular crystallography. On beamline 10 at SRS (Daresbury Laboratory, UK), a versatile design has allowed test data sets to be collected at six wavelengths between 0.979 and 2.290 A in order to evaluate the importance and the interdependence of experimental variables such as the Bijvoet ratio, wavelength, resolution limit, data redundancy and absorbed X-ray dose in the sample per data set. All the samples used in the experiments were high-quality hen egg-white lysozyme crystals. X-radiation damage was found to affect disulfide bridges after the crystals had been given a total dose of 0.20 x 10(7) Gy. However, with such a total dose, it was still possible in all cases to find a strategy to collect data sets to determine the sulfur substructure and produce good-quality phases by choosing an optimum combination of wavelength, exposure time and redundancy. A |Delta(ano)|/sigma(Delta(ano)) greater than 1.5 for all resolution shells was a necessary requirement for successful sulfur SAD substructure location. Provided this is achieved, it seems possible to find an optimum compromise between wavelength, redundancy and dose to provide phasing information. The choice of the wavelength should then follow the sample composition and the diffracting properties of the crystal. For strongly diffracting crystals, wavelengths equal or shorter than 1.540 A can be selected to capture the available data (provided the Bijvoet ratio is reasonable), while a longer wavelength, to gain as high a Bijvoet ratio as possible, must be used for more weakly diffracting crystals. These results suggest that an approach to a sulfur SAD experiment based on a complete description of the crystal system and the instrument for data collection is useful.

The interdependence of wavelength, redundancy and dose in sulfur SAD experiments.,Cianci M, Helliwell JR, Suzuki A Acta Crystallogr D Biol Crystallogr. 2008 Dec;64(Pt 12):1196-209. Epub, 2008 Nov 18. PMID:19018096^[2]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

↑ Maehashi K, Matano M, Irisawa T, Uchino M, Kashiwagi Y, Watanabe T. Molecular characterization of goose- and chicken-type lysozymes in emu (Dromaius novaehollandiae): evidence for extremely low lysozyme levels in emu egg white. Gene. 2012 Jan 15;492(1):244-9. doi: 10.1016/j.gene.2011.10.021. Epub 2011 Oct, 25. PMID:22044478 doi:10.1016/j.gene.2011.10.021
↑ Cianci M, Helliwell JR, Suzuki A. The interdependence of wavelength, redundancy and dose in sulfur SAD experiments. Acta Crystallogr D Biol Crystallogr. 2008 Dec;64(Pt 12):1196-209. Epub, 2008 Nov 18. PMID:19018096 doi:10.1107/S0907444908030503

1 Structural highlights
2 Function
3 Evolutionary Conservation
4 Publication Abstract from PubMed
5 See Also
6 References

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2w1x"

@@ Line 1: / Line 1: @@
-==THE INTERDEPENDENCE OF WAVELENGTH, REDUNDANCY AND DOSE IN SULFUR SAD EXPERIMENTS: 1.284 A WAVELENGTH 360 IMAGES DATA==
-<StructureSection load='2w1x' size='340' side='right' caption='[[2w1x]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
+==The interdependence of wavelength, redundancy and dose in sulfur SAD experiments: 1.284 A wavelength 360 images data==
+<StructureSection load='2w1x' size='340' side='right'caption='[[2w1x]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2w1x]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W1X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W1X FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2w1x]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W1X OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2W1X FirstGlance]. <br>
-</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene><br>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1w6z|1w6z]], [[1kxx|1kxx]], [[4lyo|4lyo]], [[3lyo|3lyo]], [[1kip|1kip]], [[1t6v|1t6v]], [[1ic7|1ic7]], [[1vds|1vds]], [[1lzt|1lzt]], [[1kir|1kir]], [[1lys|1lys]], [[1e8l|1e8l]], [[1bwj|1bwj]], [[132l|132l]], [[1yil|1yil]], [[1heo|1heo]], [[1sfg|1sfg]], [[1kxw|1kxw]], [[2c8o|2c8o]], [[1yl1|1yl1]], [[1sf4|1sf4]], [[1g7l|1g7l]], [[1ior|1ior]], [[1h87|1h87]], [[1ljg|1ljg]], [[3lyt|3lyt]], [[1iot|1iot]], [[1dpx|1dpx]], [[1v7s|1v7s]], [[1ja6|1ja6]], [[1jis|1jis]], [[1ir8|1ir8]], [[2w1m|2w1m]], [[1uic|1uic]], [[1ykz|1ykz]], [[1xgq|1xgq]], [[1uie|1uie]], [[1lji|1lji]], [[1lj3|1lj3]], [[8lyz|8lyz]], [[1dpw|1dpw]], [[1bwi|1bwi]], [[2iff|2iff]], [[2lyo|2lyo]], [[1g7h|1g7h]], [[1jj0|1jj0]], [[1lks|1lks]], [[1rfp|1rfp]], [[5lyt|5lyt]], [[1sfb|1sfb]], [[1jiy|1jiy]], [[1ir7|1ir7]], [[1iee|1iee]], [[1xei|1xei]], [[1xek|1xek]], [[1hel|1hel]], [[1at6|1at6]], [[1ljf|1ljf]], [[1mlc|1mlc]], [[1f10|1f10]], [[2b5z|2b5z]], [[1lsz|1lsz]], [[193l|193l]], [[1ljk|1ljk]], [[1sq2|1sq2]], [[6lyt|6lyt]], [[1vdq|1vdq]], [[1zmy|1zmy]], [[1lje|1lje]], [[2d91|2d91]], [[1b2k|1b2k]], [[1lze|1lze]], [[1aki|1aki]], [[1uia|1uia]], [[1hen|1hen]], [[1yik|1yik]], [[1xfp|1xfp]], [[2d6b|2d6b]], [[1lpi|1lpi]], [[1ndg|1ndg]], [[1lsd|1lsd]], [[1flw|1flw]], [[2blx|2blx]], [[6lyz|6lyz]], [[1lsg|1lsg]], [[1nbz|1nbz]], [[4lyt|4lyt]], [[3hfm|3hfm]], [[1ved|1ved]], [[1jit|1jit]], [[1lzn|1lzn]], [[1wtn|1wtn]], [[1uuz|1uuz]], [[1lyz|1lyz]], [[1ja2|1ja2]], [[2d4i|2d4i]], [[2fbb|2fbb]], [[2lym|2lym]], [[1fdl|1fdl]], [[1lz9|1lz9]], [[1lse|1lse]], [[1lzh|1lzh]], [[1gxx|1gxx]], [[1lsm|1lsm]], [[1jj3|1jj3]], [[3lym|3lym]], [[7lyz|7lyz]], [[1yky|1yky]], [[1heq|1heq]], [[1kiq|1kiq]], [[1t3p|1t3p]], [[1uih|1uih]], [[1kxy|1kxy]], [[2lzh|2lzh]], [[2w1l|2w1l]], [[1g7j|1g7j]], [[1b0d|1b0d]], [[2bly|2bly]], [[1bhz|1bhz]], [[1her|1her]], [[1wtm|1wtm]], [[1hep|1hep]], [[1ioq|1ioq]], [[1nby|1nby]], [[1jtt|1jtt]], [[1qio|1qio]], [[1lza|1lza]], [[1ps5|1ps5]], [[1xgp|1xgp]], [[1gwd|1gwd]], [[1jpo|1jpo]], [[1v7t|1v7t]], [[1h6m|1h6m]], [[2a7d|2a7d]], [[1j1p|1j1p]], [[1dqj|1dqj]], [[2c8p|2c8p]], [[1z55|1z55]], [[1ljj|1ljj]], [[1lsb|1lsb]], [[1f0w|1f0w]], [[1flq|1flq]], [[1lzg|1lzg]], [[1lzc|1lzc]], [[1jj1|1jj1]], [[1rcm|1rcm]], [[1yqv|1yqv]], [[1uid|1uid]], [[1hsx|1hsx]], [[1bgi|1bgi]], [[1lzd|1lzd]], [[1lcn|1lcn]], [[1hew|1hew]], [[2cds|2cds]], [[2vb1|2vb1]], [[2aub|2aub]], [[1uib|1uib]], [[1hf4|1hf4]], [[1j1x|1j1x]], [[1ir9|1ir9]], [[1rjc|1rjc]], [[1ios|1ios]], [[2cgi|2cgi]], [[1uc0|1uc0]], [[1azf|1azf]], [[1ljh|1ljh]], [[1ic4|1ic4]], [[4lyz|4lyz]], [[1gpq|1gpq]], [[2a6u|2a6u]], [[2d4k|2d4k]], [[1xej|1xej]], [[1ja7|1ja7]], [[1mel|1mel]], [[1ri8|1ri8]], [[1uig|1uig]], [[1bvx|1bvx]], [[1qtk|1qtk]], [[1c10|1c10]], [[1lkr|1lkr]], [[1lyo|1lyo]], [[1n4f|1n4f]], [[1hsw|1hsw]], [[1g7m|1g7m]], [[1jto|1jto]], [[2w1y|2w1y]], [[1sf7|1sf7]], [[1lsf|1lsf]], [[1fn5|1fn5]], [[5lyz|5lyz]], [[2d4j|2d4j]], [[3lzt|3lzt]], [[1c08|1c08]], [[1ndm|1ndm]], [[1sf6|1sf6]], [[3lyz|3lyz]], [[1bvk|1bvk]], [[1uif|1uif]], [[1vau|1vau]], [[2lyz|2lyz]], [[1fly|1fly]], [[1lma|1lma]], [[1j1o|1j1o]], [[1hc0|1hc0]], [[1yl0|1yl0]], [[2lzt|2lzt]], [[4lzt|4lzt]], [[1a2y|1a2y]], [[1uco|1uco]], [[1lsy|1lsy]], [[1p2c|1p2c]], [[1ic5|1ic5]], [[1gxv|1gxv]], [[5lym|5lym]], [[1lsa|1lsa]], [[1ua6|1ua6]], [[1at5|1at5]], [[1hem|1hem]], [[1lj4|1lj4]], [[1vfb|1vfb]], [[1f3j|1f3j]], [[1vat|1vat]], [[1ja4|1ja4]], [[2a7f|2a7f]], [[4lym|4lym]], [[1flu|1flu]], [[194l|194l]], [[1lz8|1lz8]], [[1ykx|1ykx]], [[2hfm|2hfm]], [[1vdt|1vdt]], [[1bwh|1bwh]], [[1io5|1io5]], [[1lsn|1lsn]], [[1g7i|1g7i]], [[1lzb|1lzb]], [[2bpu|2bpu]], [[1lsc|1lsc]], [[1vdp|1vdp]]</td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1w6z|1w6z]], [[1kxx|1kxx]], [[4lyo|4lyo]], [[3lyo|3lyo]], [[1kip|1kip]], [[1t6v|1t6v]], [[1ic7|1ic7]], [[1vds|1vds]], [[1lzt|1lzt]], [[1kir|1kir]], [[1lys|1lys]], [[1e8l|1e8l]], [[1bwj|1bwj]], [[132l|132l]], [[1yil|1yil]], [[1heo|1heo]], [[1sfg|1sfg]], [[1kxw|1kxw]], [[2c8o|2c8o]], [[1yl1|1yl1]], [[1sf4|1sf4]], [[1g7l|1g7l]], [[1ior|1ior]], [[1h87|1h87]], [[1ljg|1ljg]], [[3lyt|3lyt]], [[1iot|1iot]], [[1dpx|1dpx]], [[1v7s|1v7s]], [[1ja6|1ja6]], [[1jis|1jis]], [[1ir8|1ir8]], [[2w1m|2w1m]], [[1uic|1uic]], [[1ykz|1ykz]], [[1xgq|1xgq]], [[1uie|1uie]], [[1lji|1lji]], [[1lj3|1lj3]], [[8lyz|8lyz]], [[1dpw|1dpw]], [[1bwi|1bwi]], [[2iff|2iff]], [[2lyo|2lyo]], [[1g7h|1g7h]], [[1jj0|1jj0]], [[1lks|1lks]], [[1rfp|1rfp]], [[5lyt|5lyt]], [[1sfb|1sfb]], [[1jiy|1jiy]], [[1ir7|1ir7]], [[1iee|1iee]], [[1xei|1xei]], [[1xek|1xek]], [[1hel|1hel]], [[1at6|1at6]], [[1ljf|1ljf]], [[1mlc|1mlc]], [[1f10|1f10]], [[2b5z|2b5z]], [[1lsz|1lsz]], [[193l|193l]], [[1ljk|1ljk]], [[1sq2|1sq2]], [[6lyt|6lyt]], [[1vdq|1vdq]], [[1zmy|1zmy]], [[1lje|1lje]], [[2d91|2d91]], [[1b2k|1b2k]], [[1lze|1lze]], [[1aki|1aki]], [[1uia|1uia]], [[1hen|1hen]], [[1yik|1yik]], [[1xfp|1xfp]], [[2d6b|2d6b]], [[1lpi|1lpi]], [[1ndg|1ndg]], [[1lsd|1lsd]], [[1flw|1flw]], [[2blx|2blx]], [[6lyz|6lyz]], [[1lsg|1lsg]], [[1nbz|1nbz]], [[4lyt|4lyt]], [[3hfm|3hfm]], [[1ved|1ved]], [[1jit|1jit]], [[1lzn|1lzn]], [[1wtn|1wtn]], [[1uuz|1uuz]], [[1lyz|1lyz]], [[1ja2|1ja2]], [[2d4i|2d4i]], [[2fbb|2fbb]], [[2lym|2lym]], [[1fdl|1fdl]], [[1lz9|1lz9]], [[1lse|1lse]], [[1lzh|1lzh]], [[1gxx|1gxx]], [[1lsm|1lsm]], [[1jj3|1jj3]], [[3lym|3lym]], [[7lyz|7lyz]], [[1yky|1yky]], [[1heq|1heq]], [[1kiq|1kiq]], [[1t3p|1t3p]], [[1uih|1uih]], [[1kxy|1kxy]], [[2lzh|2lzh]], [[2w1l|2w1l]], [[1g7j|1g7j]], [[1b0d|1b0d]], [[2bly|2bly]], [[1bhz|1bhz]], [[1her|1her]], [[1wtm|1wtm]], [[1hep|1hep]], [[1ioq|1ioq]], [[1nby|1nby]], [[1jtt|1jtt]], [[1qio|1qio]], [[1lza|1lza]], [[1ps5|1ps5]], [[1xgp|1xgp]], [[1gwd|1gwd]], [[1jpo|1jpo]], [[1v7t|1v7t]], [[1h6m|1h6m]], [[2a7d|2a7d]], [[1j1p|1j1p]], [[1dqj|1dqj]], [[2c8p|2c8p]], [[1z55|1z55]], [[1ljj|1ljj]], [[1lsb|1lsb]], [[1f0w|1f0w]], [[1flq|1flq]], [[1lzg|1lzg]], [[1lzc|1lzc]], [[1jj1|1jj1]], [[1rcm|1rcm]], [[1yqv|1yqv]], [[1uid|1uid]], [[1hsx|1hsx]], [[1bgi|1bgi]], [[1lzd|1lzd]], [[1lcn|1lcn]], [[1hew|1hew]], [[2cds|2cds]], [[2vb1|2vb1]], [[2aub|2aub]], [[1uib|1uib]], [[1hf4|1hf4]], [[1j1x|1j1x]], [[1ir9|1ir9]], [[1rjc|1rjc]], [[1ios|1ios]], [[2cgi|2cgi]], [[1uc0|1uc0]], [[1azf|1azf]], [[1ljh|1ljh]], [[1ic4|1ic4]], [[4lyz|4lyz]], [[1gpq|1gpq]], [[2a6u|2a6u]], [[2d4k|2d4k]], [[1xej|1xej]], [[1ja7|1ja7]], [[1mel|1mel]], [[1ri8|1ri8]], [[1uig|1uig]], [[1bvx|1bvx]], [[1qtk|1qtk]], [[1c10|1c10]], [[1lkr|1lkr]], [[1lyo|1lyo]], [[1n4f|1n4f]], [[1hsw|1hsw]], [[1g7m|1g7m]], [[1jto|1jto]], [[2w1y|2w1y]], [[1sf7|1sf7]], [[1lsf|1lsf]], [[1fn5|1fn5]], [[5lyz|5lyz]], [[2d4j|2d4j]], [[3lzt|3lzt]], [[1c08|1c08]], [[1ndm|1ndm]], [[1sf6|1sf6]], [[3lyz|3lyz]], [[1bvk|1bvk]], [[1uif|1uif]], [[1vau|1vau]], [[2lyz|2lyz]], [[1fly|1fly]], [[1lma|1lma]], [[1j1o|1j1o]], [[1hc0|1hc0]], [[1yl0|1yl0]], [[2lzt|2lzt]], [[4lzt|4lzt]], [[1a2y|1a2y]], [[1uco|1uco]], [[1lsy|1lsy]], [[1p2c|1p2c]], [[1ic5|1ic5]], [[1gxv|1gxv]], [[5lym|5lym]], [[1lsa|1lsa]], [[1ua6|1ua6]], [[1at5|1at5]], [[1hem|1hem]], [[1lj4|1lj4]], [[1vfb|1vfb]], [[1f3j|1f3j]], [[1vat|1vat]], [[1ja4|1ja4]], [[2a7f|2a7f]], [[4lym|4lym]], [[1flu|1flu]], [[194l|194l]], [[1lz8|1lz8]], [[1ykx|1ykx]], [[2hfm|2hfm]], [[1vdt|1vdt]], [[1bwh|1bwh]], [[1io5|1io5]], [[1lsn|1lsn]], [[1g7i|1g7i]], [[1lzb|1lzb]], [[2bpu|2bpu]], [[1lsc|1lsc]], [[1vdp|1vdp]]</div></td></tr>
-<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
-<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w1x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w1x OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w1x RCSB], [http://www.ebi.ac.uk/pdbsum/2w1x PDBsum]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2w1x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w1x OCA], [http://pdbe.org/2w1x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2w1x RCSB], [http://www.ebi.ac.uk/pdbsum/2w1x PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2w1x ProSAT]</span></td></tr>
-<table>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
 Check<jmol>
   <jmolCheckbox>
-    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w1/2w1x_consurf.spt"</scriptWhenChecked>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w1/2w1x_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
-</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2w1x ConSurf].
 <div style="clear:both"></div>
 <div style="background-color:#fffaf0;">
@@ Line 26: / Line 29: @@
 From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 </div>
+<div class="pdbe-citations 2w1x" style="background-color:#fffaf0;"></div>
 ==See Also==
@@ Line 34: / Line 38: @@
 </StructureSection>
 [[Category: Gallus gallus]]
+[[Category: Large Structures]]
 [[Category: Lysozyme]]
-[[Category: Cianci, M.]]
+[[Category: Cianci, M]]
-[[Category: Helliwell, J R.]]
+[[Category: Helliwell, J R]]
-[[Category: Suzuki, A.]]
+[[Category: Suzuki, A]]
 [[Category: Detector- tilt geometry]]
 [[Category: Dose]]

2w1x

From Proteopedia

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The interdependence of wavelength, redundancy and dose in sulfur SAD experiments: 1.284 A wavelength 360 images data

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Evolutionary Conservation

Publication Abstract from PubMed

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