2qor

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==Crystal structure of Plasmodium vivax guanylate kinase==
==Crystal structure of Plasmodium vivax guanylate kinase==
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<StructureSection load='2qor' size='340' side='right' caption='[[2qor]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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<StructureSection load='2qor' size='340' side='right'caption='[[2qor]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2qor]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_vivax Plasmodium vivax]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QOR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QOR FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2qor]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_vivax Plasmodium vivax]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QOR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QOR FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5GP:GUANOSINE-5-MONOPHOSPHATE'>5GP</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5GP:GUANOSINE-5-MONOPHOSPHATE'>5GP</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1gky|1gky]], [[1ex6|1ex6]], [[1ex7|1ex7]], [[2anc|2anc]], [[2anb|2anb]], [[2an9|2an9]], [[2f3r|2f3r]], [[1s96|1s96]], [[2f3t|2f3t]], [[1znw|1znw]], [[1znx|1znx]], [[1zny|1zny]], [[1s4q|1s4q]], [[1znz|1znz]], [[1z8f|1z8f]], [[1z6g|1z6g]], [[1lvg|1lvg]], [[2j41|2j41]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qor FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qor OCA], [https://pdbe.org/2qor PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qor RCSB], [https://www.ebi.ac.uk/pdbsum/2qor PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qor ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Pv099895, PVX_099895 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5855 Plasmodium vivax])</td></tr>
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</table>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Guanylate_kinase Guanylate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.8 2.7.4.8] </span></td></tr>
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== Function ==
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qor FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qor OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2qor RCSB], [http://www.ebi.ac.uk/pdbsum/2qor PDBsum]</span></td></tr>
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[https://www.uniprot.org/uniprot/A5K709_PLAVS A5K709_PLAVS]
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<table>
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== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qo/2qor_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qo/2qor_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qor ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Guanylate kinase|Guanylate kinase]]
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*[[Guanylate kinase 3D structures|Guanylate kinase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Guanylate kinase]]
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[[Category: Large Structures]]
[[Category: Plasmodium vivax]]
[[Category: Plasmodium vivax]]
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[[Category: Merritt, E A.]]
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[[Category: Le Trong I]]
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[[Category: SGPP, Structural Genomics of Pathogenic Protozoa Consortium.]]
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[[Category: Merritt EA]]
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[[Category: Trong, I Le.]]
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[[Category: Kinase]]
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[[Category: Phosphotransferase]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Purine metabolism]]
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[[Category: Sgpp]]
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[[Category: Structural genomic]]
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[[Category: Structural genomics of pathogenic protozoa consortium]]
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[[Category: Transferase]]
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Current revision

Crystal structure of Plasmodium vivax guanylate kinase

PDB ID 2qor

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