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2z2e
From Proteopedia
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==Crystal Structure of Canine Milk Lysozyme Stabilized against Non-enzymatic Deamidation== | ==Crystal Structure of Canine Milk Lysozyme Stabilized against Non-enzymatic Deamidation== | ||
| - | <StructureSection load='2z2e' size='340' side='right' caption='[[2z2e]], [[Resolution|resolution]] 2.01Å' scene=''> | + | <StructureSection load='2z2e' size='340' side='right'caption='[[2z2e]], [[Resolution|resolution]] 2.01Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2z2e]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2z2e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Canis_lupus_familiaris Canis lupus familiaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z2E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z2E FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.01Å</td></tr> |
| - | <tr><td class="sblockLbl"><b> | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z2e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z2e OCA], [https://pdbe.org/2z2e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z2e RCSB], [https://www.ebi.ac.uk/pdbsum/2z2e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z2e ProSAT]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/LYSC1_CANLF LYSC1_CANLF] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.[PROSITE-ProRule:PRU00680] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z2/2z2e_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z2/2z2e_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2z2e ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 2z2e" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Canis lupus familiaris]] | [[Category: Canis lupus familiaris]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Aizawa | + | [[Category: Aizawa T]] |
| - | [[Category: Akieda | + | [[Category: Akieda D]] |
| - | [[Category: Demura | + | [[Category: Demura M]] |
| - | [[Category: Kamiya | + | [[Category: Kamiya M]] |
| - | [[Category: Kawano | + | [[Category: Kawano K]] |
| - | [[Category: Nitta | + | [[Category: Nitta K]] |
| - | [[Category: Nonaka | + | [[Category: Nonaka Y]] |
| - | [[Category: Tanaka | + | [[Category: Tanaka I]] |
| - | [[Category: Watanabe | + | [[Category: Watanabe N]] |
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Current revision
Crystal Structure of Canine Milk Lysozyme Stabilized against Non-enzymatic Deamidation
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Categories: Canis lupus familiaris | Large Structures | Aizawa T | Akieda D | Demura M | Kamiya M | Kawano K | Nitta K | Nonaka Y | Tanaka I | Watanabe N
