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2pwp
From Proteopedia
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==Crystal structure of spermidine synthase from Plasmodium falciparum in complex with spermidine== | ==Crystal structure of spermidine synthase from Plasmodium falciparum in complex with spermidine== | ||
| - | <StructureSection load='2pwp' size='340' side='right' caption='[[2pwp]], [[Resolution|resolution]] 2.10Å' scene=''> | + | <StructureSection load='2pwp' size='340' side='right'caption='[[2pwp]], [[Resolution|resolution]] 2.10Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2pwp]] is a 3 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2pwp]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PWP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PWP FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=SPD:SPERMIDINE'>SPD</scene></td></tr> | |
| - | <tr><td class="sblockLbl"><b>[[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pwp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pwp OCA], [https://pdbe.org/2pwp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pwp RCSB], [https://www.ebi.ac.uk/pdbsum/2pwp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pwp ProSAT]</span></td></tr> |
| - | < | + | </table> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | == Function == |
| - | <table> | + | [https://www.uniprot.org/uniprot/Q8II73_PLAF7 Q8II73_PLAF7] |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pw/2pwp_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pw/2pwp_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pwp ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Spermidine | + | *[[Spermidine synthase 3D structures|Spermidine synthase 3D structures]] |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Plasmodium falciparum 3D7]] |
| - | [[Category: Arrowsmith | + | [[Category: Arrowsmith CH]] |
| - | [[Category: Bochkarev | + | [[Category: Bochkarev A]] |
| - | [[Category: Dong | + | [[Category: Dong A]] |
| - | [[Category: Edwards | + | [[Category: Edwards AM]] |
| - | [[Category: Hui | + | [[Category: Hui R]] |
| - | [[Category: Kozieradzki | + | [[Category: Kozieradzki I]] |
| - | [[Category: Lew | + | [[Category: Lew J]] |
| - | [[Category: Plotnikov | + | [[Category: Plotnikov AN]] |
| - | [[Category: Qiu | + | [[Category: Qiu W]] |
| - | [[Category: Ren | + | [[Category: Ren H]] |
| - | + | [[Category: Schapira M]] | |
| - | [[Category: Schapira | + | [[Category: Sundstrom M]] |
| - | [[Category: Sundstrom | + | [[Category: Vedadi M]] |
| - | [[Category: Vedadi | + | [[Category: Wasney G]] |
| - | [[Category: Wasney | + | [[Category: Weigelt J]] |
| - | [[Category: Weigelt | + | [[Category: Wu H]] |
| - | [[Category: Wu | + | [[Category: Zhao Y]] |
| - | [[Category: Zhao | + | |
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Current revision
Crystal structure of spermidine synthase from Plasmodium falciparum in complex with spermidine
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Categories: Large Structures | Plasmodium falciparum 3D7 | Arrowsmith CH | Bochkarev A | Dong A | Edwards AM | Hui R | Kozieradzki I | Lew J | Plotnikov AN | Qiu W | Ren H | Schapira M | Sundstrom M | Vedadi M | Wasney G | Weigelt J | Wu H | Zhao Y
