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2wwa

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==CRYO-EM STRUCTURE OF IDLE YEAST SSH1 COMPLEX BOUND TO THE YEAST 80S RIBOSOME==
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<StructureSection load='2wwa' size='340' side='right' caption='[[2wwa]], [[Resolution|resolution]] 8.90&Aring;' scene=''>
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==Cryo-EM structure of idle yeast Ssh1 complex bound to the yeast 80S ribosome==
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<SX load='2wwa' size='340' side='right' viewer='molstar' caption='[[2wwa]], [[Resolution|resolution]] 8.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2wwa]] is a 15 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WWA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WWA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2wwa]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WWA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WWA FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1k5y|1k5y]], [[1s1i|1s1i]], [[2wwb|2wwb]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 8.9&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wwa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wwa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wwa RCSB], [http://www.ebi.ac.uk/pdbsum/2wwa PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wwa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wwa OCA], [https://pdbe.org/2wwa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wwa RCSB], [https://www.ebi.ac.uk/pdbsum/2wwa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wwa ProSAT]</span></td></tr>
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<table>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SSH1_YEAST SSH1_YEAST] Part of the Ssh1 complex, which probably is the major component of a channel-forming translocon complex that may function exclusively in the cotranslational pathway of protein endoplasmic reticulum (ER) import.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ww/2wwa_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ww/2wwa_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wwa ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2wwa" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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<references/>
<references/>
__TOC__
__TOC__
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</StructureSection>
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</SX>
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[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Armache, J P.]]
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[[Category: Armache JP]]
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[[Category: Becker, T.]]
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[[Category: Becker T]]
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[[Category: Beckmann, R.]]
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[[Category: Beckmann R]]
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[[Category: Berninghausen, O.]]
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[[Category: Berninghausen O]]
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[[Category: Bhushan, S.]]
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[[Category: Bhushan S]]
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[[Category: Funes, S.]]
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[[Category: Funes S]]
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[[Category: Gilmore, R.]]
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[[Category: Gilmore R]]
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[[Category: Gumbart, J.]]
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[[Category: Gumbart J]]
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[[Category: Jarasch, A.]]
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[[Category: Jarasch A]]
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[[Category: Jossinet, F.]]
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[[Category: Jossinet F]]
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[[Category: Mandon, E.]]
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[[Category: Mandon E]]
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[[Category: Mielke, T.]]
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[[Category: Mielke T]]
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[[Category: Schulten, K.]]
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[[Category: Schulten K]]
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[[Category: Westhof, E.]]
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[[Category: Westhof E]]
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[[Category: Cotranslational protein translocation]]
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[[Category: Endoplasmic reticulum]]
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[[Category: Isopeptide bond]]
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[[Category: Membrane]]
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[[Category: Phosphoprotein]]
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[[Category: Protein conducting channel]]
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[[Category: Protein exit tunnel]]
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[[Category: Protein transport]]
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[[Category: Ribonucleoprotein]]
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[[Category: Ribosomal protein]]
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[[Category: Ribosome]]
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[[Category: Rna-binding]]
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[[Category: Rrna-binding]]
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[[Category: Signal sequence]]
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[[Category: Translocation]]
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[[Category: Transmembrane]]
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[[Category: Transport]]
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Current revision

Cryo-EM structure of idle yeast Ssh1 complex bound to the yeast 80S ribosome

2wwa, resolution 8.90Å

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