2vm6

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:01, 9 May 2024) (edit) (undo)
 
(6 intermediate revisions not shown.)
Line 1: Line 1:
-
==HUMAN BCL2-A1 IN COMPLEX WITH BIM-BH3 PEPTIDE==
+
 
-
<StructureSection load='2vm6' size='340' side='right' caption='[[2vm6]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
+
==Human Bcl2-A1 in complex with Bim-BH3 peptide==
 +
<StructureSection load='2vm6' size='340' side='right'caption='[[2vm6]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2vm6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VM6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VM6 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2vm6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VM6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VM6 FirstGlance]. <br>
-
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
-
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2vm5|2vm5]], [[2v6q|2v6q]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vm6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vm6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vm6 RCSB], [http://www.ebi.ac.uk/pdbsum/2vm6 PDBsum]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vm6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vm6 OCA], [https://pdbe.org/2vm6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vm6 RCSB], [https://www.ebi.ac.uk/pdbsum/2vm6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vm6 ProSAT]</span></td></tr>
-
<table>
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/B2LA1_HUMAN B2LA1_HUMAN] Retards apoptosis induced by IL-3 deprivation. May function in the response of hemopoietic cells to external signals and in maintaining endothelial survival during infection (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
-
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vm/2vm6_consurf.spt"</scriptWhenChecked>
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vm/2vm6_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
-
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2vm6 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
Line 25: Line 28:
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
 +
<div class="pdbe-citations 2vm6" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
-
*[[Bcl-2|Bcl-2]]
+
*[[B-cell lymphoma proteins 3D structures|B-cell lymphoma proteins 3D structures]]
== References ==
== References ==
<references/>
<references/>
Line 33: Line 37:
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Arrowsmith, C H.]]
+
[[Category: Large Structures]]
-
[[Category: Berg, S Van Den.]]
+
[[Category: Arrowsmith CH]]
-
[[Category: Berglund, H.]]
+
[[Category: Berglund H]]
-
[[Category: Busam, R D.]]
+
[[Category: Busam RD]]
-
[[Category: Collins, R.]]
+
[[Category: Collins R]]
-
[[Category: Dahlgren, L G.]]
+
[[Category: Dahlgren LG]]
-
[[Category: Edwards, A M.]]
+
[[Category: Edwards AM]]
-
[[Category: Flodin, S.]]
+
[[Category: Flodin S]]
-
[[Category: Flores, A.]]
+
[[Category: Flores A]]
-
[[Category: Graslund, S.]]
+
[[Category: Graslund S]]
-
[[Category: Hammarstrom, M.]]
+
[[Category: Hammarstrom M]]
-
[[Category: Herman, M D.]]
+
[[Category: Herman MD]]
-
[[Category: Johansson, I.]]
+
[[Category: Johansson I]]
-
[[Category: Kallas, A.]]
+
[[Category: Kallas A]]
-
[[Category: Karlberg, T.]]
+
[[Category: Karlberg T]]
-
[[Category: Kotenyova, T.]]
+
[[Category: Kotenyova T]]
-
[[Category: Lehtio, L.]]
+
[[Category: Lehtio L]]
-
[[Category: Moche, M.]]
+
[[Category: Moche M]]
-
[[Category: Nilsson, M E.]]
+
[[Category: Nilsson ME]]
-
[[Category: Nordlund, P.]]
+
[[Category: Nordlund P]]
-
[[Category: Nyman, T.]]
+
[[Category: Nyman T]]
-
[[Category: Persson, C.]]
+
[[Category: Persson C]]
-
[[Category: Sagemark, J.]]
+
[[Category: Sagemark J]]
-
[[Category: Sgc, Structural Genomics Consortium.]]
+
[[Category: Svensson L]]
-
[[Category: Svensson, L.]]
+
[[Category: Thorsell AG]]
-
[[Category: Thorsell, A G.]]
+
[[Category: Tresaugues L]]
-
[[Category: Tresaugues, L.]]
+
[[Category: Weigelt J]]
-
[[Category: Weigelt, J.]]
+
[[Category: Welin M]]
-
[[Category: Welin, M.]]
+
[[Category: Van den Berg S]]
-
[[Category: Antiapoptotic]]
+
-
[[Category: Apoptosis]]
+
-
[[Category: B-cell lymphoma2]]
+
-
[[Category: Bcl-2a1]]
+
-
[[Category: Bcl2a1]]
+
-
[[Category: Bfl-1]]
+
-
[[Category: Bim]]
+
-
[[Category: Immune system]]
+
-
[[Category: Membrane]]
+

Current revision

Human Bcl2-A1 in complex with Bim-BH3 peptide

PDB ID 2vm6

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2vm6"
Personal tools