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3huh
From Proteopedia
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==The structure of biphenyl-2,3-diol 1,2-dioxygenase iii-related protein from salmonella typhimurium== | ==The structure of biphenyl-2,3-diol 1,2-dioxygenase iii-related protein from salmonella typhimurium== | ||
| - | <StructureSection load='3huh' size='340' side='right' caption='[[3huh]], [[Resolution|resolution]] 1.50Å' scene=''> | + | <StructureSection load='3huh' size='340' side='right'caption='[[3huh]], [[Resolution|resolution]] 1.50Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3huh]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3huh]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HUH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HUH FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5Å</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3huh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3huh OCA], [https://pdbe.org/3huh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3huh RCSB], [https://www.ebi.ac.uk/pdbsum/3huh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3huh ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/3huh TOPSAN]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/VIR17_SALTY VIR17_SALTY] Is critically involved in promoting the replication of S.typhimurium cells inside host macrophages, suggesting a role in the establishment of bacterial colonization within macrophages. May be involved in the biosynthesis and modification of the peptidoglycan layer of the cell wall.<ref>PMID:16893888</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hu/3huh_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hu/3huh_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3huh ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
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| + | ==See Also== | ||
| + | *[[Dioxygenase 3D structures|Dioxygenase 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Salmonella enterica subsp. enterica serovar | + | [[Category: Large Structures]] |
| - | [[Category: Almo | + | [[Category: Salmonella enterica subsp. enterica serovar Typhimurium]] |
| - | [[Category: Burley | + | [[Category: Almo SC]] |
| - | [[Category: Fedorov | + | [[Category: Burley SK]] |
| - | [[Category: Fedorov | + | [[Category: Fedorov AA]] |
| - | + | [[Category: Fedorov EV]] | |
| - | [[Category: Sauder | + | [[Category: Sauder JM]] |
| - | [[Category: Toro | + | [[Category: Toro R]] |
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Current revision
The structure of biphenyl-2,3-diol 1,2-dioxygenase iii-related protein from salmonella typhimurium
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