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3ial

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==Giardia lamblia Prolyl-tRNA synthetase in complex with prolyl-adenylate==
==Giardia lamblia Prolyl-tRNA synthetase in complex with prolyl-adenylate==
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<StructureSection load='3ial' size='340' side='right' caption='[[3ial]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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<StructureSection load='3ial' size='340' side='right'caption='[[3ial]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3ial]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Giardia_lamblia_atcc_50803 Giardia lamblia atcc 50803]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IAL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IAL FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3ial]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Giardia_lamblia_ATCC_50803 Giardia lamblia ATCC 50803]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IAL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IAL FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PR8:5-O-[(R)-HYDROXY{[(2S)-PYRROLIDIN-2-YLCARBONYL]OXY}PHOSPHORYL]ADENOSINE'>PR8</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GL50803_15983, ProRS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=184922 Giardia lamblia ATCC 50803])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PR8:5-O-[(R)-HYDROXY{[(2S)-PYRROLIDIN-2-YLCARBONYL]OXY}PHOSPHORYL]ADENOSINE'>PR8</scene></td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Proline--tRNA_ligase Proline--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.15 6.1.1.15] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ial FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ial OCA], [https://pdbe.org/3ial PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ial RCSB], [https://www.ebi.ac.uk/pdbsum/3ial PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ial ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ial FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ial OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ial RCSB], [http://www.ebi.ac.uk/pdbsum/3ial PDBsum]</span></td></tr>
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</table>
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<table>
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== Function ==
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[https://www.uniprot.org/uniprot/A8BR89_GIAIC A8BR89_GIAIC]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ia/3ial_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ia/3ial_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ial ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3ial" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Aminoacyl tRNA Synthetase|Aminoacyl tRNA Synthetase]]
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*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Giardia lamblia atcc 50803]]
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[[Category: Giardia lamblia ATCC 50803]]
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[[Category: Proline--tRNA ligase]]
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[[Category: Large Structures]]
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[[Category: Larson, E T.]]
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[[Category: Larson ET]]
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[[Category: Merritt, E A.]]
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[[Category: Protozoa, Medical Structural Genomics of Pathogenic.]]
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[[Category: Aar]]
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[[Category: Aminoacyl-trna synthetase]]
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[[Category: Atp-binding]]
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[[Category: Cysr]]
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[[Category: Ligase]]
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[[Category: Medical structural genomics of pathogenic protazoa]]
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[[Category: Medical structural genomics of pathogenic protozoa]]
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[[Category: Msgpp]]
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[[Category: Nucleotide-binding]]
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[[Category: Pror]]
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[[Category: Structural genomic]]
[[Category: Structural genomic]]
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[[Category: Translation]]
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[[Category: Merritt EA]]
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[[Category: Trna ligase]]
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Current revision

Giardia lamblia Prolyl-tRNA synthetase in complex with prolyl-adenylate

PDB ID 3ial

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