1sl8

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==Calcium-loaded apo-aequorin from Aequorea victoria==
==Calcium-loaded apo-aequorin from Aequorea victoria==
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<StructureSection load='1sl8' size='340' side='right' caption='[[1sl8]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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<StructureSection load='1sl8' size='340' side='right'caption='[[1sl8]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1sl8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aequorea_victoria Aequorea victoria]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SL8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1SL8 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1sl8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aequorea_victoria Aequorea victoria]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SL8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SL8 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1el4|1el4]], [[1ej3|1ej3]], [[1jf0|1jf0]], [[1jf2|1jf2]], [[1qv0|1qv0]], [[1s36|1s36]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1sl8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sl8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1sl8 RCSB], [http://www.ebi.ac.uk/pdbsum/1sl8 PDBsum], [http://www.topsan.org/Proteins/SECSG/1sl8 TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sl8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sl8 OCA], [https://pdbe.org/1sl8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sl8 RCSB], [https://www.ebi.ac.uk/pdbsum/1sl8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sl8 ProSAT], [https://www.topsan.org/Proteins/SECSG/1sl8 TOPSAN]</span></td></tr>
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<table>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/AEQ1_AEQVI AEQ1_AEQVI] Ca(2+)-dependent bioluminescence photoprotein. Displays an emission peak at 470 nm (blue light). Trace amounts of calcium ion trigger the intramolecular oxidation of the chromophore, coelenterazine into coelenteramide and CO(2) with the concomitant emission of light.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sl/1sl8_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sl/1sl8_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sl8 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 1sl8" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Aequorea victoria]]
[[Category: Aequorea victoria]]
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[[Category: Deng, L.]]
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[[Category: Large Structures]]
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[[Category: Lee, J.]]
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[[Category: Deng L]]
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[[Category: Liu, Z J.]]
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[[Category: Lee J]]
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[[Category: Markova, S V.]]
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[[Category: Liu ZJ]]
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[[Category: Rose, J.]]
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[[Category: Markova SV]]
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[[Category: SECSG, Southeast Collaboratory for Structural Genomics.]]
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[[Category: Rose J]]
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[[Category: Vysotski, E S.]]
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[[Category: Vysotski ES]]
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[[Category: Wang, B C.]]
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[[Category: Wang BC]]
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[[Category: Aequorin]]
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[[Category: Bioluminescence]]
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[[Category: Calcium binding]]
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[[Category: Ef-hand]]
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[[Category: Luminescent protein]]
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[[Category: Obelin]]
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[[Category: Photoprotein]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Secsg]]
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[[Category: Southeast collaboratory for structural genomic]]
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[[Category: Structural genomic]]
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Current revision

Calcium-loaded apo-aequorin from Aequorea victoria

PDB ID 1sl8

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