1rxl
From Proteopedia
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==Solution structure of the engineered protein Afae-dsc== | ==Solution structure of the engineered protein Afae-dsc== | ||
- | <StructureSection load='1rxl' size='340' side='right' caption='[[1rxl | + | <StructureSection load='1rxl' size='340' side='right'caption='[[1rxl]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[1rxl]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1rxl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RXL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RXL FirstGlance]. <br> |
- | </td></tr><tr><td class="sblockLbl"><b>[[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 15 models</td></tr> |
- | <tr | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rxl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rxl OCA], [https://pdbe.org/1rxl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rxl RCSB], [https://www.ebi.ac.uk/pdbsum/1rxl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rxl ProSAT]</span></td></tr> |
- | + | </table> | |
- | <table> | + | == Function == |
+ | [https://www.uniprot.org/uniprot/AFAE3_ECOLX AFAE3_ECOLX] Hemagglutinins of uropathogenic E.coli mediate adherence to the upper urinary tract. These adhesins bind to the Dr blood group antigen and also agglutinate human erythrocytes in the presence of D-mannose (mannose-resistant hemagglutination (MRHA)). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
- | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rx/1rxl_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rx/1rxl_consurf.spt"</scriptWhenChecked> |
- | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/ | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> |
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
- | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1rxl ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
+ | <div class="pdbe-citations 1rxl" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
- | [[Category: | + | [[Category: Large Structures]] |
- | [[Category: | + | [[Category: Anderson KL]] |
- | [[Category: | + | [[Category: Barlow PN]] |
- | [[Category: | + | [[Category: Billington J]] |
- | [[Category: Chen | + | [[Category: Chen HA]] |
- | [[Category: Cota | + | [[Category: Cota E]] |
- | [[Category: | + | [[Category: Le Bouguenec C]] |
- | [[Category: | + | [[Category: Lea SM]] |
- | [[Category: | + | [[Category: Matthews S]] |
- | [[Category: | + | [[Category: Medof ME]] |
- | [[Category: Nowicki | + | [[Category: Nowicki B]] |
- | [[Category: Pettigrew | + | [[Category: Pettigrew D]] |
- | [[Category: Roversi | + | [[Category: Roversi P]] |
- | [[Category: Simpson | + | [[Category: Simpson P]] |
- | [[Category: Smith | + | [[Category: Smith RA]] |
- | [[Category: Urvil | + | [[Category: Urvil P]] |
- | [[Category: | + | [[Category: Du Merle L]] |
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Current revision
Solution structure of the engineered protein Afae-dsc
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Categories: Escherichia coli | Large Structures | Anderson KL | Barlow PN | Billington J | Chen HA | Cota E | Le Bouguenec C | Lea SM | Matthews S | Medof ME | Nowicki B | Pettigrew D | Roversi P | Simpson P | Smith RA | Urvil P | Du Merle L