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1wcg

From Proteopedia

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Current revision (13:28, 13 December 2023) (edit) (undo)
 
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==APHID MYROSINASE==
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<StructureSection load='1wcg' size='340' side='right' caption='[[1wcg]], [[Resolution|resolution]] 1.10&Aring;' scene=''>
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==Aphid myrosinase==
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<StructureSection load='1wcg' size='340' side='right'caption='[[1wcg]], [[Resolution|resolution]] 1.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1wcg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Brevicoryne_brassicae Brevicoryne brassicae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WCG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WCG FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1wcg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Brevicoryne_brassicae Brevicoryne brassicae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WCG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WCG FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.1&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thioglucosidase Thioglucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.147 3.2.1.147] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wcg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wcg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1wcg RCSB], [http://www.ebi.ac.uk/pdbsum/1wcg PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wcg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wcg OCA], [https://pdbe.org/1wcg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wcg RCSB], [https://www.ebi.ac.uk/pdbsum/1wcg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wcg ProSAT]</span></td></tr>
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<table>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/MYRO1_BREBR MYRO1_BREBR] Hydrolyzes glucosinolates to a labile aglycone. This rapidly undergoes spontaneous rearrangement, eliminating sulfur to yield a number of toxic metabolites. Thereby developing a chemical defense system that exploits and mimics the host plant.<ref>PMID:11804799</ref> <ref>PMID:17623639</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wc/1wcg_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wc/1wcg_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wcg ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 1wcg" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Brevicoryne brassicae]]
[[Category: Brevicoryne brassicae]]
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[[Category: Thioglucosidase]]
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[[Category: Large Structures]]
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[[Category: Arzt, S.]]
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[[Category: Arzt S]]
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[[Category: Bones, A M.]]
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[[Category: Bones AM]]
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[[Category: Brandt, A.]]
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[[Category: Brandt A]]
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[[Category: Burmeister, W P.]]
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[[Category: Burmeister WP]]
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[[Category: Haertel, F V.]]
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[[Category: Haertel FV]]
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[[Category: Husebye, H.]]
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[[Category: Husebye H]]
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[[Category: Rossiter, J T.]]
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[[Category: Rossiter JT]]
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[[Category: Aphid]]
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[[Category: Beta-barrel]]
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[[Category: Beta-glucosidase]]
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[[Category: Glucosidase]]
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[[Category: Glycosidase]]
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[[Category: Hydrolase]]
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[[Category: Insect]]
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[[Category: Myrosinase]]
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[[Category: Thioglucosidase]]
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Current revision

Aphid myrosinase

PDB ID 1wcg

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