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2asi

From Proteopedia

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==ASPARTIC PROTEINASE==
==ASPARTIC PROTEINASE==
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<StructureSection load='2asi' size='340' side='right' caption='[[2asi]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
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<StructureSection load='2asi' size='340' side='right'caption='[[2asi]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2asi]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhizomucor_miehei Rhizomucor miehei]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1asi 1asi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ASI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ASI FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2asi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhizomucor_miehei Rhizomucor miehei]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1asi 1asi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ASI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ASI FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mucorpepsin Mucorpepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.23 3.4.23.23] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2asi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2asi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2asi RCSB], [http://www.ebi.ac.uk/pdbsum/2asi PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2asi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2asi OCA], [https://pdbe.org/2asi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2asi RCSB], [https://www.ebi.ac.uk/pdbsum/2asi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2asi ProSAT]</span></td></tr>
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<table>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CARP_RHIMI CARP_RHIMI] This enzyme, capable of clotting milk is frequently used for cheese production.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/as/2asi_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/as/2asi_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2asi ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2asi" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Proteinase|Proteinase]]
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*[[Proteinase 3D structures|Proteinase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Mucorpepsin]]
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[[Category: Large Structures]]
[[Category: Rhizomucor miehei]]
[[Category: Rhizomucor miehei]]
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[[Category: Jia, Z.]]
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[[Category: Jia Z]]
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[[Category: Kepliakov, P S.A.]]
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[[Category: Kepliakov PSA]]
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[[Category: Quail, J W.]]
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[[Category: Quail JW]]
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[[Category: Vandonselaar, M.]]
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[[Category: Vandonselaar M]]
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[[Category: Yang, J.]]
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[[Category: Yang J]]
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[[Category: Aspartyl protease]]
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[[Category: Glycoprotein]]
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[[Category: Hydrolase]]
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[[Category: Zymogen]]
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Current revision

ASPARTIC PROTEINASE

PDB ID 2asi

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