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2c7b

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==THE CRYSTAL STRUCTURE OF ESTE1, A NEW THERMOPHILIC AND THERMOSTABLE CARBOXYLESTERASE CLONED FROM A METAGENOMIC LIBRARY==
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<StructureSection load='2c7b' size='340' side='right' caption='[[2c7b]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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==The Crystal Structure of EstE1, a New Thermophilic and Thermostable Carboxylesterase Cloned from a Metagenomic Library==
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<StructureSection load='2c7b' size='340' side='right'caption='[[2c7b]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2c7b]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Uncultured_archaeon Uncultured archaeon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C7B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C7B FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2c7b]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Uncultured_archaeon Uncultured archaeon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C7B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2C7B FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2bzq|2bzq]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carboxylesterase Carboxylesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.1 3.1.1.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2c7b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c7b OCA], [https://pdbe.org/2c7b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2c7b RCSB], [https://www.ebi.ac.uk/pdbsum/2c7b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2c7b ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c7b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c7b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2c7b RCSB], [http://www.ebi.ac.uk/pdbsum/2c7b PDBsum]</span></td></tr>
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</table>
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<table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q5G935_UNCAX Q5G935_UNCAX]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c7/2c7b_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c7/2c7b_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2c7b ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2c7b" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Carboxylesterase|Carboxylesterase]]
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*[[Carboxylesterase 3D structures|Carboxylesterase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Carboxylesterase]]
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[[Category: Large Structures]]
[[Category: Uncultured archaeon]]
[[Category: Uncultured archaeon]]
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[[Category: Byun, J S.]]
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[[Category: Byun J-S]]
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[[Category: Cho, H S.]]
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[[Category: Cho H-S]]
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[[Category: Kim, D U.]]
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[[Category: Kim D-U]]
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[[Category: Oh, J W.]]
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[[Category: Oh J-W]]
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[[Category: Rhee, J K.]]
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[[Category: Rhee J-K]]
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[[Category: Alpha/beta hydrolase fold]]
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[[Category: Carboxyesterase]]
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[[Category: Hsl]]
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[[Category: Hydrolase]]
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[[Category: Thermophilic enzyme]]
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Current revision

The Crystal Structure of EstE1, a New Thermophilic and Thermostable Carboxylesterase Cloned from a Metagenomic Library

PDB ID 2c7b

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