2b46

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==Crystal structure of an engineered uninhibited Bacillus subtilis xylanase in substrate bound state==
==Crystal structure of an engineered uninhibited Bacillus subtilis xylanase in substrate bound state==
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<StructureSection load='2b46' size='340' side='right' caption='[[2b46]], [[Resolution|resolution]] 2.21&Aring;' scene=''>
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<StructureSection load='2b46' size='340' side='right'caption='[[2b46]], [[Resolution|resolution]] 2.21&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2b46]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B46 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2B46 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2b46]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B46 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B46 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.215&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1t6e|1t6e]], [[1t6g|1t6g]], [[2b42|2b42]], [[2b45|2b45]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PRD_900116:4beta-beta-xylobiose'>PRD_900116</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">xynA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 Bacillus subtilis])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b46 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b46 OCA], [https://pdbe.org/2b46 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b46 RCSB], [https://www.ebi.ac.uk/pdbsum/2b46 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b46 ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8] </span></td></tr>
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</table>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2b46 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b46 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2b46 RCSB], [http://www.ebi.ac.uk/pdbsum/2b46 PDBsum]</span></td></tr>
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== Function ==
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<table>
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[https://www.uniprot.org/uniprot/XYNA_BACSU XYNA_BACSU]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b4/2b46_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b4/2b46_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2b46 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
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[[Category: Endo-1,4-beta-xylanase]]
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[[Category: Large Structures]]
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[[Category: Brijs, K.]]
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[[Category: Brijs K]]
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[[Category: Courtin, C M.]]
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[[Category: Courtin CM]]
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[[Category: Delcour, J A.]]
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[[Category: De Ranter CJ]]
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[[Category: Dewilde, M.]]
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[[Category: Delcour JA]]
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[[Category: Gebruers, K.]]
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[[Category: Dewilde M]]
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[[Category: Rabijns, A.]]
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[[Category: Gebruers K]]
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[[Category: Ranter, C J.De.]]
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[[Category: Rabijns A]]
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[[Category: Sansen, S.]]
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[[Category: Sansen S]]
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[[Category: Sibbesen, O.]]
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[[Category: Sibbesen O]]
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[[Category: Sorensen, J F.]]
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[[Category: Sorensen JF]]
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[[Category: Beta-jelly roll structure]]
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[[Category: Hydrolase]]
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Current revision

Crystal structure of an engineered uninhibited Bacillus subtilis xylanase in substrate bound state

PDB ID 2b46

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