2b3w
From Proteopedia
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==NMR structure of the E.coli protein YbiA, Northeast Structural Genomics target ET24.== | ==NMR structure of the E.coli protein YbiA, Northeast Structural Genomics target ET24.== | ||
| - | <StructureSection load='2b3w' size='340' side='right' caption='[[2b3w | + | <StructureSection load='2b3w' size='340' side='right'caption='[[2b3w]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2b3w]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2b3w]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B3W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B3W FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b3w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b3w OCA], [https://pdbe.org/2b3w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b3w RCSB], [https://www.ebi.ac.uk/pdbsum/2b3w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b3w ProSAT], [https://www.topsan.org/Proteins/NESGC/2b3w TOPSAN]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RIBX_ECOLI RIBX_ECOLI] Catalyzes the hydrolysis of the N-glycosidic bond in the first two intermediates of riboflavin biosynthesis, which are highly reactive metabolites, yielding relatively innocuous products. Thus, can divert a surplus of harmful intermediates into relatively harmless products and pre-empt the damage these intermediates would otherwise do. Helps maintain flavin levels. May act on other substrates in vivo. Has no activity against GTP, nucleoside monophosphates or ADP-ribose (PubMed:25431972). Is Required for swarming motility (PubMed:17122336).<ref>PMID:17122336</ref> <ref>PMID:25431972</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b3/2b3w_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b3/2b3w_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2b3w ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Acton TB]] |
| - | [[Category: | + | [[Category: Cort JR]] |
| - | [[Category: | + | [[Category: Kennedy MA]] |
| - | [[Category: | + | [[Category: Montelione GT]] |
| - | [[Category: Ramelot | + | [[Category: Ramelot TA]] |
| - | [[Category: Shih | + | [[Category: Shih LY]] |
| - | [[Category: Xiao | + | [[Category: Xiao R]] |
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Current revision
NMR structure of the E.coli protein YbiA, Northeast Structural Genomics target ET24.
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Categories: Escherichia coli | Large Structures | Acton TB | Cort JR | Kennedy MA | Montelione GT | Ramelot TA | Shih LY | Xiao R
