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2a2j
From Proteopedia
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<StructureSection load='2a2j' size='340' side='right' caption='[[2a2j]], [[Resolution|resolution]] 2.50Å' scene=''> | <StructureSection load='2a2j' size='340' side='right' caption='[[2a2j]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2a2j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2a2j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A2J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2A2J FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr> | + | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pyridoxal_5'-phosphate_synthase Pyridoxal 5'-phosphate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.3.5 1.4.3.5] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pyridoxal_5'-phosphate_synthase Pyridoxal 5'-phosphate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.3.5 1.4.3.5] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2a2j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a2j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2a2j RCSB], [http://www.ebi.ac.uk/pdbsum/2a2j PDBsum], [http://www.topsan.org/Proteins/TBSGC/2a2j TOPSAN]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2a2j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a2j OCA], [http://pdbe.org/2a2j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2a2j RCSB], [http://www.ebi.ac.uk/pdbsum/2a2j PDBsum], [http://www.topsan.org/Proteins/TBSGC/2a2j TOPSAN]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PDXH_MYCTU PDXH_MYCTU]] Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity).[HAMAP-Rule:MF_01629] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2a2j ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 2a2j" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Mycobacterium tuberculosis]] | ||
[[Category: Pyridoxal 5'-phosphate synthase]] | [[Category: Pyridoxal 5'-phosphate synthase]] | ||
| - | [[Category: Hung, L W | + | [[Category: Hung, L W]] |
| - | [[Category: Kim, C Y | + | [[Category: Kim, C Y]] |
| - | [[Category: Kim, S I | + | [[Category: Kim, S I]] |
| - | [[Category: Lekin, T P | + | [[Category: Lekin, T P]] |
| - | [[Category: Pedelacq, J D | + | [[Category: Pedelacq, J D]] |
| - | [[Category: Rho, B S | + | [[Category: Rho, B S]] |
| - | [[Category: Rupp, B | + | [[Category: Rupp, B]] |
| - | [[Category: Segelke, B W | + | [[Category: Segelke, B W]] |
| - | [[Category: Terwilliger, T C | + | [[Category: Terwilliger, T C]] |
| - | [[Category: Waldo, G S | + | [[Category: Waldo, G S]] |
| - | [[Category: XMTB, Mycobacterium Tuberculosis Structural Proteomics Project | + | [[Category: XMTB, Mycobacterium Tuberculosis Structural Proteomics Project]] |
[[Category: Beta barrel]] | [[Category: Beta barrel]] | ||
[[Category: Mycobacterium tuberculosis structural proteomics project]] | [[Category: Mycobacterium tuberculosis structural proteomics project]] | ||
Current revision
Crystal structure of a putative pyridoxine 5'-phosphate oxidase (Rv2607) from Mycobacterium tuberculosis
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Categories: Pyridoxal 5'-phosphate synthase | Hung, L W | Kim, C Y | Kim, S I | Lekin, T P | Pedelacq, J D | Rho, B S | Rupp, B | Segelke, B W | Terwilliger, T C | Waldo, G S | XMTB, Mycobacterium Tuberculosis Structural Proteomics Project | Beta barrel | Mycobacterium tuberculosis structural proteomics project | Oxidoreductase | Structural genomic | Xmtb
