This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2err

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (06:55, 9 March 2022) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
 +
==NMR Structure of the RNA Binding Domain of Human Fox-1 in Complex with UGCAUGU==
==NMR Structure of the RNA Binding Domain of Human Fox-1 in Complex with UGCAUGU==
-
<StructureSection load='2err' size='340' side='right' caption='[[2err]], [[NMR_Ensembles_of_Models | 30 NMR models]]' scene=''>
+
<StructureSection load='2err' size='340' side='right'caption='[[2err]], [[NMR_Ensembles_of_Models | 30 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2err]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ERR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ERR FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2err]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ERR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ERR FirstGlance]. <br>
-
</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">A2BP1, A2BP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
+
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">A2BP1, A2BP ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2err FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2err OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2err RCSB], [http://www.ebi.ac.uk/pdbsum/2err PDBsum]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2err FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2err OCA], [https://pdbe.org/2err PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2err RCSB], [https://www.ebi.ac.uk/pdbsum/2err PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2err ProSAT]</span></td></tr>
-
<table>
+
</table>
 +
== Function ==
 +
[[https://www.uniprot.org/uniprot/RFOX1_HUMAN RFOX1_HUMAN]] RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis.<ref>PMID:16537540</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
-
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/er/2err_consurf.spt"</scriptWhenChecked>
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/er/2err_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
-
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2err ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
Line 24: Line 27:
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
 +
<div class="pdbe-citations 2err" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Homo sapiens]]
+
[[Category: Human]]
-
[[Category: Allain, F H.]]
+
[[Category: Large Structures]]
-
[[Category: Auweter, S D.]]
+
[[Category: Allain, F H]]
 +
[[Category: Auweter, S D]]
[[Category: Protein-rna complex]]
[[Category: Protein-rna complex]]
[[Category: Rna binding protein]]
[[Category: Rna binding protein]]

Current revision

NMR Structure of the RNA Binding Domain of Human Fox-1 in Complex with UGCAUGU

PDB ID 2err

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2err"
Personal tools