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2kj8

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==NMR structure of fragment 87-196 from the putative phage integrase IntS of E. coli: Northeast Structural Genomics Consortium target ER652A, PSI-2==
==NMR structure of fragment 87-196 from the putative phage integrase IntS of E. coli: Northeast Structural Genomics Consortium target ER652A, PSI-2==
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<StructureSection load='2kj8' size='340' side='right' caption='[[2kj8]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2kj8' size='340' side='right'caption='[[2kj8]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2kj8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KJ8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KJ8 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2kj8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KJ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KJ8 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">b2349, intC, intS, JW2345, yfdB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 Escherichia coli K-12])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kj8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kj8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2kj8 RCSB], [http://www.ebi.ac.uk/pdbsum/2kj8 PDBsum], [http://www.topsan.org/Proteins/NESGC/2kj8 TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kj8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kj8 OCA], [https://pdbe.org/2kj8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kj8 RCSB], [https://www.ebi.ac.uk/pdbsum/2kj8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kj8 ProSAT], [https://www.topsan.org/Proteins/NESGC/2kj8 TOPSAN]</span></td></tr>
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<table>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/INTS_ECOLI INTS_ECOLI] Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kj/2kj8_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kj/2kj8_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2kj8 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Escherichia coli k-12]]
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[[Category: Escherichia coli K-12]]
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[[Category: Ciccosanti, C.]]
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[[Category: Large Structures]]
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[[Category: Cort, J R.]]
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[[Category: Ciccosanti C]]
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[[Category: Everett, J K.]]
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[[Category: Cort JR]]
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[[Category: Janjua, H.]]
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[[Category: Everett JK]]
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[[Category: Kennedy, M A.]]
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[[Category: Janjua H]]
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[[Category: Montelione, G T.]]
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[[Category: Kennedy MA]]
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[[Category: NESG, Northeast Structural Genomics Consortium.]]
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[[Category: Montelione GT]]
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[[Category: Nair, R.]]
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[[Category: Nair R]]
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[[Category: Ramelot, T A.]]
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[[Category: Ramelot TA]]
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[[Category: Rost, B.]]
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[[Category: Rost B]]
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[[Category: Swapna, G.]]
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[[Category: Swapna G]]
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[[Category: Wang, D.]]
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[[Category: Wang D]]
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[[Category: Xiao, R.]]
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[[Category: Xiao R]]
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[[Category: Cps-53]]
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[[Category: Dna binding protein]]
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[[Category: Dna integration]]
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[[Category: Dna recombination]]
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[[Category: Intc]]
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[[Category: Integrase]]
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[[Category: Int]]
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[[Category: Nesg]]
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[[Category: Northeast structural genomics consortium]]
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[[Category: Protein structure initiative]]
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[[Category: Psi-2]]
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[[Category: Structural genomic]]
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[[Category: Unknown function]]
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[[Category: Yfdb]]
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Current revision

NMR structure of fragment 87-196 from the putative phage integrase IntS of E. coli: Northeast Structural Genomics Consortium target ER652A, PSI-2

PDB ID 2kj8

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