2k9a

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==The Solution Structure of the Arl2 Effector, BART==
==The Solution Structure of the Arl2 Effector, BART==
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<StructureSection load='2k9a' size='340' side='right' caption='[[2k9a]], [[NMR_Ensembles_of_Models | 50 NMR models]]' scene=''>
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<StructureSection load='2k9a' size='340' side='right'caption='[[2k9a]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2k9a]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K9A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2K9A FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2k9a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K9A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K9A FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ARL2BP, BART, BART1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k9a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k9a OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2k9a RCSB], [http://www.ebi.ac.uk/pdbsum/2k9a PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k9a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k9a OCA], [https://pdbe.org/2k9a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k9a RCSB], [https://www.ebi.ac.uk/pdbsum/2k9a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k9a ProSAT]</span></td></tr>
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<table>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/AR2BP_HUMAN AR2BP_HUMAN] Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2.<ref>PMID:18234692</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k9/2k9a_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k9/2k9a_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2k9a ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2k9a" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Bailey, L K.]]
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[[Category: Large Structures]]
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[[Category: Campbell, L J.]]
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[[Category: Bailey LK]]
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[[Category: Evetts, K A.]]
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[[Category: Campbell LJ]]
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[[Category: Littlefield, K.]]
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[[Category: Evetts KA]]
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[[Category: Mott, H R.]]
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[[Category: Littlefield K]]
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[[Category: Nietlispach, D.]]
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[[Category: Mott HR]]
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[[Category: Owen, D.]]
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[[Category: Nietlispach D]]
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[[Category: Rajendra, E.]]
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[[Category: Owen D]]
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[[Category: Effector]]
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[[Category: Rajendra E]]
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[[Category: Mitochondrion]]
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[[Category: Phosphoprotein]]
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[[Category: Protein]]
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[[Category: Protein binding]]
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[[Category: Small g protein]]
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Current revision

The Solution Structure of the Arl2 Effector, BART

PDB ID 2k9a

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