2hj0

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==Crystal Structure of the Putative Alfa Subunit of Citrate Lyase in Complex with Citrate from Streptococcus mutans, Northeast Structural Genomics Target SmR12 (CASP Target).==
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<StructureSection load='2hj0' size='340' side='right' caption='[[2hj0]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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==Crystal Structure of the Putative Alfa Subunit of Citrate Lyase in Complex with Citrate from Streptococcus mutans, Northeast Structural Genomics Target SmR12 .==
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<StructureSection load='2hj0' size='340' side='right'caption='[[2hj0]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2hj0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_mutans Streptococcus mutans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HJ0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HJ0 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2hj0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_mutans_UA159 Streptococcus mutans UA159]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HJ0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HJ0 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cilA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1309 Streptococcus mutans])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hj0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hj0 OCA], [https://pdbe.org/2hj0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hj0 RCSB], [https://www.ebi.ac.uk/pdbsum/2hj0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hj0 ProSAT], [https://www.topsan.org/Proteins/NESGC/2hj0 TOPSAN]</span></td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Citrate_(pro-3S)-lyase Citrate (pro-3S)-lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.3.6 4.1.3.6] </span></td></tr>
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</table>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hj0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hj0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2hj0 RCSB], [http://www.ebi.ac.uk/pdbsum/2hj0 PDBsum], [http://www.topsan.org/Proteins/NESGC/2hj0 TOPSAN]</span></td></tr>
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== Function ==
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<table>
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[https://www.uniprot.org/uniprot/Q8DUC1_STRMU Q8DUC1_STRMU]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hj/2hj0_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hj/2hj0_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hj0 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Streptococcus mutans]]
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[[Category: Large Structures]]
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[[Category: Acton, T B.]]
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[[Category: Streptococcus mutans UA159]]
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[[Category: Baran, M.]]
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[[Category: Acton TB]]
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[[Category: Cunningham, K.]]
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[[Category: Baran M]]
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[[Category: Forouhar, F.]]
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[[Category: Cunningham K]]
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[[Category: Hunt, J F.]]
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[[Category: Forouhar F]]
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[[Category: Hussain, M.]]
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[[Category: Hunt JF]]
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[[Category: Janjua, H.]]
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[[Category: Hussain M]]
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[[Category: Jayaraman, S.]]
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[[Category: Janjua H]]
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[[Category: Liu, J.]]
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[[Category: Jayaraman S]]
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[[Category: Ma, L C.]]
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[[Category: Liu J]]
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[[Category: Montelione, G T.]]
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[[Category: Ma LC]]
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[[Category: NESG, Northeast Structural Genomics Consortium.]]
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[[Category: Montelione GT]]
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[[Category: Rost, B.]]
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[[Category: Rost B]]
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[[Category: Shastry, R.]]
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[[Category: Shastry R]]
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[[Category: Tong, L.]]
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[[Category: Tong L]]
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[[Category: Xiao, R.]]
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[[Category: Xiao R]]
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[[Category: Alpha beta protein.]]
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[[Category: Lyase]]
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[[Category: Nesg]]
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[[Category: Northeast structural genomics consortium]]
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[[Category: Protein structure initiative]]
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[[Category: Psi-2]]
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[[Category: Structural genomic]]
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Current revision

Crystal Structure of the Putative Alfa Subunit of Citrate Lyase in Complex with Citrate from Streptococcus mutans, Northeast Structural Genomics Target SmR12 .

PDB ID 2hj0

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