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2jjw

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==STRUCTURE OF HUMAN SIGNAL REGULATORY PROTEIN (SIRP) GAMMA==
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<StructureSection load='2jjw' size='340' side='right' caption='[[2jjw]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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==Structure of human signal regulatory protein (sirp) gamma==
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<StructureSection load='2jjw' size='340' side='right'caption='[[2jjw]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2jjw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JJW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JJW FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2jjw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JJW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JJW FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2jju|2jju]], [[2jjv|2jjv]], [[2uv3|2uv3]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jjw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jjw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2jjw RCSB], [http://www.ebi.ac.uk/pdbsum/2jjw PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jjw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jjw OCA], [https://pdbe.org/2jjw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jjw RCSB], [https://www.ebi.ac.uk/pdbsum/2jjw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jjw ProSAT]</span></td></tr>
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<table>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SIRPG_HUMAN SIRPG_HUMAN] Probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation.<ref>PMID:15383453</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jj/2jjw_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jj/2jjw_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jjw ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2jjw" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Barclay, A N.]]
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[[Category: Large Structures]]
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[[Category: Graham, S C.]]
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[[Category: Barclay AN]]
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[[Category: Harlos, K.]]
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[[Category: Graham SC]]
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[[Category: Hatherley, D.]]
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[[Category: Harlos K]]
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[[Category: Stuart, D I.]]
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[[Category: Hatherley D]]
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[[Category: Turner, J.]]
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[[Category: Stuart DI]]
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[[Category: Cell adhesion]]
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[[Category: Turner J]]
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[[Category: Glycoprotein]]
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[[Category: Immunoglobulin domain]]
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[[Category: Immunoglobulin superfamily]]
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[[Category: Membrane]]
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[[Category: Paired receptor]]
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[[Category: Signal regulatory protein gamma]]
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[[Category: Sirp]]
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[[Category: Sirpg]]
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[[Category: Transmembrane]]
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Current revision

Structure of human signal regulatory protein (sirp) gamma

PDB ID 2jjw

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