2k0q

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==Solution structure of CopK, a periplasmic protein involved in copper resistance in Cupriavidus metallidurans CH34==
==Solution structure of CopK, a periplasmic protein involved in copper resistance in Cupriavidus metallidurans CH34==
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<StructureSection load='2k0q' size='340' side='right' caption='[[2k0q]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2k0q' size='340' side='right'caption='[[2k0q]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2k0q]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cupriavidus_metallidurans Cupriavidus metallidurans]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K0Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2K0Q FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2k0q]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cupriavidus_metallidurans_CH34 Cupriavidus metallidurans CH34]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K0Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K0Q FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">copK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=119219 Cupriavidus metallidurans])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k0q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k0q OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2k0q RCSB], [http://www.ebi.ac.uk/pdbsum/2k0q PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k0q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k0q OCA], [https://pdbe.org/2k0q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k0q RCSB], [https://www.ebi.ac.uk/pdbsum/2k0q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k0q ProSAT]</span></td></tr>
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<table>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/COPK_CUPMC COPK_CUPMC] Involved in resistance to copper. Can bind up to 2 copper ions. Has higher affinity for Cu(+) than for Cu(2+).<ref>PMID:18533181</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k0/2k0q_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k0/2k0q_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2k0q ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2k0q" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Cupriavidus metallidurans]]
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[[Category: Cupriavidus metallidurans CH34]]
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[[Category: Aelst, S van.]]
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[[Category: Large Structures]]
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[[Category: Bersch, B.]]
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[[Category: Bersch B]]
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[[Category: Coves, J.]]
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[[Category: Coves J]]
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[[Category: Favier, A.]]
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[[Category: Favier A]]
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[[Category: Mergeay, M.]]
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[[Category: Mergeay M]]
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[[Category: Schanda, P.]]
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[[Category: Schanda P]]
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[[Category: Vallaeys, T.]]
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[[Category: Vallaeys T]]
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[[Category: Wattiez, R.]]
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[[Category: Wattiez R]]
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[[Category: Heavy metal resistance]]
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[[Category: Van Aelst S]]
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[[Category: Metal binding protein]]
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[[Category: Open barrel]]
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[[Category: Plasmid-encoded]]
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Current revision

Solution structure of CopK, a periplasmic protein involved in copper resistance in Cupriavidus metallidurans CH34

PDB ID 2k0q

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