2kko

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==Solution NMR structure of the homodimeric winged helix-turn-helix DNA-binding domain (fragment 1-100) Mb0332 from Mycobacterium bovis, a possible ArsR-family transcriptional regulator. Northeast Structural Genomics Consortium Target MbR242E.==
==Solution NMR structure of the homodimeric winged helix-turn-helix DNA-binding domain (fragment 1-100) Mb0332 from Mycobacterium bovis, a possible ArsR-family transcriptional regulator. Northeast Structural Genomics Consortium Target MbR242E.==
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<StructureSection load='2kko' size='340' side='right' caption='[[2kko]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2kko' size='340' side='right'caption='[[2kko]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2kko]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_bovis Mycobacterium bovis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KKO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KKO FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2kko]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_variant_bovis Mycobacterium tuberculosis variant bovis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KKO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KKO FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Mb0332 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1765 Mycobacterium bovis])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kko FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kko OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2kko RCSB], [http://www.ebi.ac.uk/pdbsum/2kko PDBsum], [http://www.topsan.org/Proteins/NESGC/2kko TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kko FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kko OCA], [https://pdbe.org/2kko PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kko RCSB], [https://www.ebi.ac.uk/pdbsum/2kko PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kko ProSAT], [https://www.topsan.org/Proteins/NESGC/2kko TOPSAN]</span></td></tr>
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<table>
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</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kk/2kko_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kk/2kko_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2kko ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Mycobacterium bovis]]
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[[Category: Large Structures]]
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[[Category: Acton, T B.]]
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[[Category: Mycobacterium tuberculosis variant bovis]]
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[[Category: Ciccosanti, C.]]
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[[Category: Acton TB]]
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[[Category: Cort, J R.]]
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[[Category: Ciccosanti C]]
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[[Category: Everett, J K.]]
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[[Category: Cort JR]]
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[[Category: Jiang, M.]]
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[[Category: Everett JK]]
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[[Category: Kennedy, M A.]]
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[[Category: Jiang M]]
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[[Category: Montelione, G T.]]
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[[Category: Kennedy MA]]
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[[Category: NESG, Northeast Structural Genomics Consortium.]]
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[[Category: Montelione GT]]
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[[Category: Nair, R.]]
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[[Category: Nair R]]
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[[Category: Ramelot, T A.]]
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[[Category: Ramelot TA]]
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[[Category: Rost, B.]]
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[[Category: Rost B]]
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[[Category: Swapna, G.]]
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[[Category: Swapna G]]
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[[Category: Wang, D.]]
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[[Category: Wang D]]
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[[Category: Xiao, R.]]
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[[Category: Xiao R]]
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[[Category: Dna binding protein]]
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[[Category: Dna-binding]]
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[[Category: Homodimer]]
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[[Category: Nesg]]
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[[Category: Northeast structural genomics consortium]]
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[[Category: Protein structure initiative]]
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[[Category: Psi-2]]
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[[Category: Structural genomic]]
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[[Category: Transcription]]
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[[Category: Transcription regulation]]
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[[Category: Transcriptional regulator]]
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[[Category: Transferase]]
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[[Category: Whth]]
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[[Category: Winged helix-turn-helix]]
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Current revision

Solution NMR structure of the homodimeric winged helix-turn-helix DNA-binding domain (fragment 1-100) Mb0332 from Mycobacterium bovis, a possible ArsR-family transcriptional regulator. Northeast Structural Genomics Consortium Target MbR242E.

PDB ID 2kko

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