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2plf

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==The structure of aIF2gamma subunit from the archaeon Sulfolobus solfataricus in the nucleotide-free form.==
==The structure of aIF2gamma subunit from the archaeon Sulfolobus solfataricus in the nucleotide-free form.==
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<StructureSection load='2plf' size='340' side='right' caption='[[2plf]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
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<StructureSection load='2plf' size='340' side='right'caption='[[2plf]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2plf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PLF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PLF FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2plf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus Saccharolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PLF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PLF FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2aho|2aho]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">eif2g ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 Sulfolobus solfataricus])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2plf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2plf OCA], [https://pdbe.org/2plf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2plf RCSB], [https://www.ebi.ac.uk/pdbsum/2plf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2plf ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2plf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2plf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2plf RCSB], [http://www.ebi.ac.uk/pdbsum/2plf PDBsum]</span></td></tr>
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</table>
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<table>
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== Function ==
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[https://www.uniprot.org/uniprot/IF2G_SACS2 IF2G_SACS2] eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.[HAMAP-Rule:MF_00119]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pl/2plf_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pl/2plf_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2plf ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2plf" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Sulfolobus solfataricus]]
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[[Category: Large Structures]]
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[[Category: Blaesi, U.]]
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[[Category: Saccharolobus solfataricus]]
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[[Category: Fedorov, R V.]]
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[[Category: Blaesi U]]
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[[Category: Garber, M B.]]
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[[Category: Fedorov RV]]
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[[Category: Hasenohrl, D.]]
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[[Category: Garber MB]]
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[[Category: Manstein, D J.]]
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[[Category: Hasenohrl D]]
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[[Category: Nikonov, O S.]]
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[[Category: Manstein DJ]]
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[[Category: Nikonov, S V.]]
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[[Category: Nikonov OS]]
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[[Category: Nikulin, A D.]]
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[[Category: Nikonov SV]]
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[[Category: Stolboushkina, E A.]]
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[[Category: Nikulin AD]]
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[[Category: Aif2]]
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[[Category: Stolboushkina EA]]
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[[Category: Initiation factor 2 gamma subunit]]
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[[Category: Initiation of the translation]]
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[[Category: Nucleotide binding]]
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[[Category: Translation]]
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Current revision

The structure of aIF2gamma subunit from the archaeon Sulfolobus solfataricus in the nucleotide-free form.

PDB ID 2plf

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