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2vjv

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==CRYSTAL STRUCTURE OF THE IS608 TRANSPOSASE IN COMPLEX WITH LEFT END 26-MER DNA HAIRPIN AND A 6-MER DNA REPRESENTING THE LEFT END CLEAVAGE SITE==
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<StructureSection load='2vjv' size='340' side='right' caption='[[2vjv]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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==Crystal structure of the IS608 transposase in complex with left end 26-mer DNA hairpin and a 6-mer DNA representing the left end cleavage site==
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<StructureSection load='2vjv' size='340' side='right'caption='[[2vjv]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2vjv]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VJV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VJV FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2vjv]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VJV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VJV FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2a6m|2a6m]], [[2a6o|2a6o]], [[2vju|2vju]], [[2vhg|2vhg]], [[2vic|2vic]], [[2vih|2vih]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vjv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vjv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vjv RCSB], [http://www.ebi.ac.uk/pdbsum/2vjv PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vjv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vjv OCA], [https://pdbe.org/2vjv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vjv RCSB], [https://www.ebi.ac.uk/pdbsum/2vjv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vjv ProSAT]</span></td></tr>
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<table>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q933Z0_HELPX Q933Z0_HELPX]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vj/2vjv_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vj/2vjv_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2vjv ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2vjv" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Transposase 3D structures|Transposase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Helicobacter pylori]]
[[Category: Helicobacter pylori]]
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[[Category: Barabas, O.]]
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[[Category: Large Structures]]
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[[Category: Chandler, M.]]
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[[Category: Barabas O]]
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[[Category: Dyda, F.]]
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[[Category: Chandler M]]
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[[Category: Guynet, C.]]
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[[Category: Dyda F]]
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[[Category: Hickman, A B.]]
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[[Category: Guynet C]]
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[[Category: Ronning, D R.]]
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[[Category: Hickman AB]]
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[[Category: Ton-Hoang, B.]]
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[[Category: Ronning DR]]
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[[Category: Dna stem loop]]
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[[Category: Ton-Hoang B]]
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[[Category: Dna-binding protein]]
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[[Category: Huh motif]]
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[[Category: Protein-dna complex]]
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[[Category: Transposition]]
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Current revision

Crystal structure of the IS608 transposase in complex with left end 26-mer DNA hairpin and a 6-mer DNA representing the left end cleavage site

PDB ID 2vjv

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