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1ihp

From Proteopedia

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[[Image:1ihp.jpg|left|200px]]
 
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{{Structure
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==STRUCTURE OF PHOSPHOMONOESTERASE==
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|PDB= 1ihp |SIZE=350|CAPTION= <scene name='initialview01'>1ihp</scene>, resolution 2.5&Aring;
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<StructureSection load='1ihp' size='340' side='right'caption='[[1ihp]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=SO4:SULFATE ION'>SO4</scene>
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<table><tr><td colspan='2'>[[1ihp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aspergillus_ficuum Aspergillus ficuum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IHP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IHP FirstGlance]. <br>
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|ACTIVITY= [http://en.wikipedia.org/wiki/3-phytase 3-phytase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.8 3.1.3.8]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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|GENE=
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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}}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ihp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ihp OCA], [https://pdbe.org/1ihp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ihp RCSB], [https://www.ebi.ac.uk/pdbsum/1ihp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ihp ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PHYA_ASPNG PHYA_ASPNG] Catalyzes the hydrolysis of inorganic orthophosphate from phytate.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ih/1ihp_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ihp ConSurf].
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<div style="clear:both"></div>
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'''STRUCTURE OF PHOSPHOMONOESTERASE'''
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==See Also==
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*[[Phytase 3D structures|Phytase 3D structures]]
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__TOC__
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==Overview==
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</StructureSection>
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Phytase is a high molecular weight acid phosphatase. The structure has an alpha/beta-domain similar to that of rat acid phosphatase and an alpha-domain with a new fold.
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==About this Structure==
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1IHP is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Aspergillus_ficuum Aspergillus ficuum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IHP OCA].
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==Reference==
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Crystal structure of phytase from Aspergillus ficuum at 2.5 A resolution., Kostrewa D, Gruninger-Leitch F, D'Arcy A, Broger C, Mitchell D, van Loon AP, Nat Struct Biol. 1997 Mar;4(3):185-90. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9164457 9164457]
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[[Category: 3-phytase]]
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[[Category: Aspergillus ficuum]]
[[Category: Aspergillus ficuum]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Kostrewa, D.]]
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[[Category: Kostrewa D]]
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[[Category: SO4]]
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[[Category: glycoprotein]]
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[[Category: hydrolase]]
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[[Category: phosphomonoesterase]]
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[[Category: signal]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:50:35 2008''
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Current revision

STRUCTURE OF PHOSPHOMONOESTERASE

PDB ID 1ihp

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