2uyq

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==CRYSTAL STRUCTURE OF ML2640C FROM MYCOBACTERIUM LEPRAE IN COMPLEX WITH S-ADENOSYLMETHIONINE==
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<StructureSection load='2uyq' size='340' side='right' caption='[[2uyq]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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==Crystal structure of ML2640c from Mycobacterium leprae in complex with S-adenosylmethionine==
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<StructureSection load='2uyq' size='340' side='right'caption='[[2uyq]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2uyq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_leprae Mycobacterium leprae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UYQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2UYQ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2uyq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_leprae Mycobacterium leprae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UYQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2UYQ FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ckd|2ckd]], [[2uyo|2uyo]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2uyq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uyq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2uyq RCSB], [http://www.ebi.ac.uk/pdbsum/2uyq PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2uyq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uyq OCA], [https://pdbe.org/2uyq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2uyq RCSB], [https://www.ebi.ac.uk/pdbsum/2uyq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2uyq ProSAT]</span></td></tr>
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<table>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Y2640_MYCLE Y2640_MYCLE] Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.<ref>PMID:17660248</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uy/2uyq_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uy/2uyq_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2uyq ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2uyq" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Mycobacterium leprae]]
[[Category: Mycobacterium leprae]]
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[[Category: Alzari, P M.]]
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[[Category: Alzari PM]]
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[[Category: Buschiazzo, A.]]
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[[Category: Buschiazzo A]]
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[[Category: Grana, M.]]
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[[Category: Grana M]]
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[[Category: Haouz, A.]]
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[[Category: Haouz A]]
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[[Category: Miras, I.]]
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[[Category: Miras I]]
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[[Category: Shepard, W.]]
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[[Category: Shepard W]]
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[[Category: Wehenkel, A.]]
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[[Category: Wehenkel A]]
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[[Category: Hypothetical protein]]
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[[Category: Putative methyltransferase]]
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[[Category: Transferase]]
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Current revision

Crystal structure of ML2640c from Mycobacterium leprae in complex with S-adenosylmethionine

PDB ID 2uyq

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