2w41

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==CRYSTAL STRUCTURE OF PLASMODIUM FALCIPARUM GLYCEROL KINASE WITH ADP==
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<StructureSection load='2w41' size='340' side='right' caption='[[2w41]], [[Resolution|resolution]] 2.41&Aring;' scene=''>
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==Crystal structure of Plasmodium falciparum glycerol kinase with ADP==
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<StructureSection load='2w41' size='340' side='right'caption='[[2w41]], [[Resolution|resolution]] 2.41&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2w41]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W41 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W41 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2w41]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W41 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W41 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.41&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2w40|2w40]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glycerol_kinase Glycerol kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.30 2.7.1.30] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w41 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w41 OCA], [https://pdbe.org/2w41 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w41 RCSB], [https://www.ebi.ac.uk/pdbsum/2w41 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w41 ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w41 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w41 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w41 RCSB], [http://www.ebi.ac.uk/pdbsum/2w41 PDBsum]</span></td></tr>
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</table>
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<table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q8IDI4_PLAF7 Q8IDI4_PLAF7]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w4/2w41_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w4/2w41_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2w41 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2w41" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Glycerol kinase]]
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[[Category: Large Structures]]
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[[Category: Plasmodium falciparum]]
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[[Category: Plasmodium falciparum 3D7]]
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[[Category: Baker, D A.]]
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[[Category: Baker DA]]
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[[Category: Brannigan, J A.]]
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[[Category: Brannigan JA]]
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[[Category: Fivelman, Q L.]]
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[[Category: Fivelman QL]]
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[[Category: Polley, S D.]]
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[[Category: Polley SD]]
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[[Category: Ranford-Cartwright, L.]]
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[[Category: Ranford-Cartwright L]]
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[[Category: Schnick, C.]]
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[[Category: Schnick C]]
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[[Category: Wilkinson, A J.]]
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[[Category: Wilkinson AJ]]
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[[Category: Wilkinson, S R.]]
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[[Category: Wilkinson SR]]
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[[Category: Closed conformation]]
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[[Category: Glycerol kinase]]
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[[Category: Kinase]]
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[[Category: Malaria]]
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[[Category: Open conformation]]
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[[Category: Plasmodium]]
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[[Category: Sugar kinase/hsp70/actin superfamily]]
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[[Category: Transferase]]
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Current revision

Crystal structure of Plasmodium falciparum glycerol kinase with ADP

PDB ID 2w41

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