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2vkp
From Proteopedia
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==Crystal structure of BTB domain from BTBD6== | ==Crystal structure of BTB domain from BTBD6== | ||
| - | <StructureSection load='2vkp' size='340' side='right' caption='[[2vkp]], [[Resolution|resolution]] 1.90Å' scene=''> | + | <StructureSection load='2vkp' size='340' side='right'caption='[[2vkp]], [[Resolution|resolution]] 1.90Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2vkp]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2vkp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VKP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VKP FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vkp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vkp OCA], [https://pdbe.org/2vkp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vkp RCSB], [https://www.ebi.ac.uk/pdbsum/2vkp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vkp ProSAT]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/BTBD6_HUMAN BTBD6_HUMAN]] Adapter protein for the CUL3 E3 ubiquitin-protein ligase complex. Involved in late neuronal development and muscle formation (By similarity). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vk/2vkp_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vk/2vkp_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2vkp ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Human]] |
| - | [[Category: Arrowsmith, C H | + | [[Category: Large Structures]] |
| - | [[Category: Bunkoczi, G | + | [[Category: Arrowsmith, C H]] |
| - | [[Category: Cooper, C D.O | + | [[Category: Bunkoczi, G]] |
| - | [[Category: Delft, F von | + | [[Category: Cooper, C D.O]] |
| - | [[Category: Edwards, A | + | [[Category: Delft, F von]] |
| - | [[Category: Elkins, J M | + | [[Category: Edwards, A]] |
| - | [[Category: Filippakopoulos, P | + | [[Category: Elkins, J M]] |
| - | [[Category: Gileadi, O | + | [[Category: Filippakopoulos, P]] |
| - | [[Category: Knapp, S | + | [[Category: Gileadi, O]] |
| - | [[Category: Pike, A C.W | + | [[Category: Knapp, S]] |
| - | [[Category: Salah, E | + | [[Category: Pike, A C.W]] |
| - | [[Category: Weigelt, J | + | [[Category: Salah, E]] |
| + | [[Category: Weigelt, J]] | ||
| + | [[Category: Protein binding]] | ||
[[Category: Protein-binding]] | [[Category: Protein-binding]] | ||
Current revision
Crystal structure of BTB domain from BTBD6
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